Genome wide expression profiling of angiogenic signaling and the Heisenberg uncertainty principle

Research output: Contribution to journalReview article

7 Citations (Scopus)

Abstract

Genome wide DNA expression profiling coupled with antibody array experiments using endostatin to probe the angiogenic signaling network in human endothelial cells were performed. The results reveal constraints on the measuring process that are of a similar kind as those implied by the uncertainty principle of quantum mechanics as described by Werner Heisenberg. We describe this analogy and argue for its heuristic utility in the conceptualization of angiogenesis as an important step in tumor formation.

Original languageEnglish (US)
Pages (from-to)1348-1351
Number of pages4
JournalCell Cycle
Volume3
Issue number11
DOIs
StatePublished - Jan 1 2004

Fingerprint

Endostatins
DNA Fingerprinting
Mechanics
Uncertainty
Endothelial Cells
Genome
Antibodies
Neoplasms
Heuristics

Keywords

  • Angiogenesis
  • Endostatin
  • Expression profiling
  • Heisenberg uncertainty
  • Signaling

ASJC Scopus subject areas

  • Molecular Biology
  • Developmental Biology
  • Cell Biology

Cite this

Genome wide expression profiling of angiogenic signaling and the Heisenberg uncertainty principle. / Huber, Peter; Hauser, Kai; Abdollahi, Amir.

In: Cell Cycle, Vol. 3, No. 11, 01.01.2004, p. 1348-1351.

Research output: Contribution to journalReview article

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