Gut Microbes’ Impact on Oncogenic Drivers: Location Matters

Michael G. White; Jennifer A. Wargo

doi:10.1016/j.molcel.2020.08.021

Gut Microbes’ Impact on Oncogenic Drivers: Location Matters

Research output: Contribution to journal › Comment/debate › peer-review

Abstract

Recent work by Kadosh et al. (2020) suggests that mutant p53 activity in gut epithelia is influenced by local production of microbial metabolites. The switch of p53 from tumor suppressor to oncogene is location-dependent and is impacted by microbially derived gallic acid.

Original language	English (US)
Pages (from-to)	878-880
Number of pages	3
Journal	Molecular cell
Volume	79
Issue number	6
DOIs	https://doi.org/10.1016/j.molcel.2020.08.021
State	Published - Sep 17 2020

ASJC Scopus subject areas

Molecular Biology
Cell Biology

Access to Document

10.1016/j.molcel.2020.08.021

Cite this

@article{a93e363032664bbeb72a1cd4bb4a8200,

title = "Gut Microbes{\textquoteright} Impact on Oncogenic Drivers: Location Matters",

abstract = "Recent work by Kadosh et al. (2020) suggests that mutant p53 activity in gut epithelia is influenced by local production of microbial metabolites. The switch of p53 from tumor suppressor to oncogene is location-dependent and is impacted by microbially derived gallic acid.",

author = "White, \{Michael G.\} and Wargo, \{Jennifer A.\}",

note = "Publisher Copyright: {\textcopyright} 2020 Elsevier Inc.",

year = "2020",

month = sep,

day = "17",

doi = "10.1016/j.molcel.2020.08.021",

language = "English (US)",

volume = "79",

pages = "878--880",

journal = "Molecular cell",

issn = "1097-2765",

publisher = "Cell Press",

number = "6",

}

TY - JOUR

T1 - Gut Microbes’ Impact on Oncogenic Drivers

T2 - Location Matters

AU - White, Michael G.

AU - Wargo, Jennifer A.

PY - 2020/9/17

Y1 - 2020/9/17

N2 - Recent work by Kadosh et al. (2020) suggests that mutant p53 activity in gut epithelia is influenced by local production of microbial metabolites. The switch of p53 from tumor suppressor to oncogene is location-dependent and is impacted by microbially derived gallic acid.

AB - Recent work by Kadosh et al. (2020) suggests that mutant p53 activity in gut epithelia is influenced by local production of microbial metabolites. The switch of p53 from tumor suppressor to oncogene is location-dependent and is impacted by microbially derived gallic acid.

UR - https://www.scopus.com/pages/publications/85090704999

UR - https://www.scopus.com/pages/publications/85090704999#tab=citedBy

U2 - 10.1016/j.molcel.2020.08.021

DO - 10.1016/j.molcel.2020.08.021

M3 - Comment/debate

C2 - 32946762

AN - SCOPUS:85090704999

SN - 1097-2765

VL - 79

SP - 878

EP - 880

JO - Molecular cell

JF - Molecular cell

IS - 6

ER -

Gut Microbes’ Impact on Oncogenic Drivers: Location Matters

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this