Gynecologic cancer intergroup (GCIG) Consensus review for mucinous ovarian carcinoma

Jonathan A. Ledermann; Daniela Luvero; Aaron Shafer; Dennis O'Connor; Giorgia Mangili; Michael Friedlander; Jacobus Pfisterer; Mansoor R. Mirza; Jae Weon Kim; Jerome Alexandre; Amit Oza; Jubilee Brown

doi:10.1097/IGC.0000000000000296

Gynecologic cancer intergroup (GCIG) Consensus review for mucinous ovarian carcinoma

Jonathan A. Ledermann, Daniela Luvero, Aaron Shafer, Dennis O'Connor, Giorgia Mangili, Michael Friedlander, Jacobus Pfisterer, Mansoor R. Mirza, Jae Weon Kim, Jerome Alexandre, Amit Oza, Jubilee Brown

Gynecological Oncology & Reproductive Medicine

Research output: Contribution to journal › Review article › peer-review

81 Scopus citations

Abstract

Mucinous carcinomas of the ovary can be primary ormetastatic in origin. Improvements in the pathological diagnosis have increased the ability to distinguish between primary andmetastatic ovarian cancers and shown that primary mucinous carcinomas are a rare subtype of ovarian cancer. Most tumors are diagnosed at an early stage, and the prognosis after surgery is good. Advanced or recurrent mucinous carcinoma of the ovary responds poorly to current cytotoxic treatments, and the prognosis is poor. Here, we review the guidelines for surgery and the results of treatment of advanced and recurrent disease. Chemotherapy with platinum and paclitaxel is currently used to treat advanced disease, but the effect of these drugs is modest, and new treatments are needed.

Original language	English (US)
Pages (from-to)	S14-S19
Journal	International Journal of Gynecological Cancer
Volume	24
Issue number	9
DOIs	https://doi.org/10.1097/IGC.0000000000000296
State	Published - Nov 2014

Keywords

Mucinous ovarian cancer
Mucinous tumor

ASJC Scopus subject areas

Oncology
Obstetrics and Gynecology

Access to Document

10.1097/IGC.0000000000000296

Cite this

@article{b82ff565da7d437ca06bba4d714ec950,

title = "Gynecologic cancer intergroup (GCIG) Consensus review for mucinous ovarian carcinoma",

abstract = "Mucinous carcinomas of the ovary can be primary ormetastatic in origin. Improvements in the pathological diagnosis have increased the ability to distinguish between primary andmetastatic ovarian cancers and shown that primary mucinous carcinomas are a rare subtype of ovarian cancer. Most tumors are diagnosed at an early stage, and the prognosis after surgery is good. Advanced or recurrent mucinous carcinoma of the ovary responds poorly to current cytotoxic treatments, and the prognosis is poor. Here, we review the guidelines for surgery and the results of treatment of advanced and recurrent disease. Chemotherapy with platinum and paclitaxel is currently used to treat advanced disease, but the effect of these drugs is modest, and new treatments are needed.",

keywords = "Mucinous ovarian cancer, Mucinous tumor",

author = "Ledermann, {Jonathan A.} and Daniela Luvero and Aaron Shafer and Dennis O'Connor and Giorgia Mangili and Michael Friedlander and Jacobus Pfisterer and Mirza, {Mansoor R.} and Kim, {Jae Weon} and Jerome Alexandre and Amit Oza and Jubilee Brown",

note = "Publisher Copyright: {\textcopyright} 2014 by IGCS and ESGO.",

year = "2014",

month = nov,

doi = "10.1097/IGC.0000000000000296",

language = "English (US)",

volume = "24",

pages = "S14--S19",

journal = "International Journal of Gynecological Cancer",

issn = "1048-891X",

publisher = "Wolters Kluwer Health",

number = "9",

}

TY - JOUR

T1 - Gynecologic cancer intergroup (GCIG) Consensus review for mucinous ovarian carcinoma

AU - Ledermann, Jonathan A.

AU - Luvero, Daniela

AU - Shafer, Aaron

AU - O'Connor, Dennis

AU - Mangili, Giorgia

AU - Friedlander, Michael

AU - Pfisterer, Jacobus

AU - Mirza, Mansoor R.

AU - Kim, Jae Weon

AU - Alexandre, Jerome

AU - Oza, Amit

AU - Brown, Jubilee

PY - 2014/11

Y1 - 2014/11

N2 - Mucinous carcinomas of the ovary can be primary ormetastatic in origin. Improvements in the pathological diagnosis have increased the ability to distinguish between primary andmetastatic ovarian cancers and shown that primary mucinous carcinomas are a rare subtype of ovarian cancer. Most tumors are diagnosed at an early stage, and the prognosis after surgery is good. Advanced or recurrent mucinous carcinoma of the ovary responds poorly to current cytotoxic treatments, and the prognosis is poor. Here, we review the guidelines for surgery and the results of treatment of advanced and recurrent disease. Chemotherapy with platinum and paclitaxel is currently used to treat advanced disease, but the effect of these drugs is modest, and new treatments are needed.

AB - Mucinous carcinomas of the ovary can be primary ormetastatic in origin. Improvements in the pathological diagnosis have increased the ability to distinguish between primary andmetastatic ovarian cancers and shown that primary mucinous carcinomas are a rare subtype of ovarian cancer. Most tumors are diagnosed at an early stage, and the prognosis after surgery is good. Advanced or recurrent mucinous carcinoma of the ovary responds poorly to current cytotoxic treatments, and the prognosis is poor. Here, we review the guidelines for surgery and the results of treatment of advanced and recurrent disease. Chemotherapy with platinum and paclitaxel is currently used to treat advanced disease, but the effect of these drugs is modest, and new treatments are needed.

KW - Mucinous ovarian cancer

KW - Mucinous tumor

UR - http://www.scopus.com/inward/record.url?scp=84988915826&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84988915826&partnerID=8YFLogxK

U2 - 10.1097/IGC.0000000000000296

DO - 10.1097/IGC.0000000000000296

M3 - Review article

C2 - 25341574

AN - SCOPUS:84988915826

SN - 1048-891X

VL - 24

SP - S14-S19

JO - International Journal of Gynecological Cancer

JF - International Journal of Gynecological Cancer

IS - 9

ER -

Gynecologic cancer intergroup (GCIG) Consensus review for mucinous ovarian carcinoma

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this