TY - GEN
T1 - Half-cone SPECT system for small animal imaging
AU - Li, Heng
AU - Zheng, Yibin
AU - Stolin, Alexander V.
AU - Kundu, Bijoy K.
AU - Williams, Mark B.
N1 - Copyright:
Copyright 2011 Elsevier B.V., All rights reserved.
PY - 2006
Y1 - 2006
N2 - Molecular imaging studies using small animals such as mice require the development of high-sensitivity, high-resolution pinhole SPECT imaging systems. It is well known that the photon detection efficiency drops remarkably as the pinhole angle increases, and spatial resolution decreases as the magnification factor decreases. To obtain high efficiency and high resolution, the pinhole should be put as close as possible to the object while the pinhole angle remains as small as possible. To address these conflicting requirements, we proposed a half-cone imaging geometry in which the detector looks at only half of the FOV in each view, while the FOV being reconstructed remain the same. Our preliminary results demonstrated that SPECT system using this geometry could achieve higher sensitivity and better spatial resolution.
AB - Molecular imaging studies using small animals such as mice require the development of high-sensitivity, high-resolution pinhole SPECT imaging systems. It is well known that the photon detection efficiency drops remarkably as the pinhole angle increases, and spatial resolution decreases as the magnification factor decreases. To obtain high efficiency and high resolution, the pinhole should be put as close as possible to the object while the pinhole angle remains as small as possible. To address these conflicting requirements, we proposed a half-cone imaging geometry in which the detector looks at only half of the FOV in each view, while the FOV being reconstructed remain the same. Our preliminary results demonstrated that SPECT system using this geometry could achieve higher sensitivity and better spatial resolution.
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M3 - Conference contribution
AN - SCOPUS:33750956915
SN - 0780395778
SN - 9780780395770
T3 - 2006 3rd IEEE International Symposium on Biomedical Imaging: From Nano to Macro - Proceedings
SP - 1236
EP - 1239
BT - 2006 3rd IEEE International Symposium on Biomedical Imaging
T2 - 2006 3rd IEEE International Symposium on Biomedical Imaging: From Nano to Macro
Y2 - 6 April 2006 through 9 April 2006
ER -