Hepatitis E virus infection after CAR T-cell treatment: An important complication in patients already facing significant health challenges

Vincent Mallet, Harrys A. Torres

Research output: Contribution to journalComment/debatepeer-review

Abstract

Cancer patients with haematological malignancies are at risk for chronic hepatitis E virus infection following chimeric antigen receptor (CAR) T-cell therapy. Strong clinical suspicion is essential for the early diagnosis and prompt treatment of this difficult-to-treat type of viral hepatitis. Commentary on: Schwarz et al. Chronic hepatitis E in a patient after CAR-T cell treatment for diffuse large B-cell lymphoma and rapid progression towards decompensated liver cirrhosis. Br J Haematol 2024 (Online ahead of print). doi: 10.1111/bjh.19892.

Original languageEnglish (US)
JournalBritish Journal of Haematology
DOIs
StateAccepted/In press - 2024

Keywords

  • CAR T-cell therapy
  • chronic hepatitis E virus
  • hematologic malignancies
  • ribavirin

ASJC Scopus subject areas

  • Hematology

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