TY - JOUR
T1 - High intensity focused ultrasound
T2 - The fundamentals, clinical applications and research trends
AU - Elhelf, I. A.Shehata
AU - Albahar, H.
AU - Shah, U.
AU - Oto, A.
AU - Cressman, E.
AU - Almekkawy, M.
N1 - Publisher Copyright:
© 2018 Société française de radiologie
PY - 2018/6
Y1 - 2018/6
N2 - Diagnostic ultrasound has been clinically used for decades. More recently, high intensity focused ultrasound (HIFU) has been developed for therapeutic use as a non-invasive technique for tissue ablation. HIFU is also being investigated for advanced applications at the cellular level. Under guidance by magnetic resonance or ultrasound imaging, HIFU can achieve precise biological effects in tissue with a high safety profile. In this article, we discuss the basic principles, advantages and limitations of HIFU. We will also address the food and drug administration (FDA) approved clinical applications in the United States and highlight active HIFU research with promising clinical outcomes.
AB - Diagnostic ultrasound has been clinically used for decades. More recently, high intensity focused ultrasound (HIFU) has been developed for therapeutic use as a non-invasive technique for tissue ablation. HIFU is also being investigated for advanced applications at the cellular level. Under guidance by magnetic resonance or ultrasound imaging, HIFU can achieve precise biological effects in tissue with a high safety profile. In this article, we discuss the basic principles, advantages and limitations of HIFU. We will also address the food and drug administration (FDA) approved clinical applications in the United States and highlight active HIFU research with promising clinical outcomes.
KW - High intensity focused ultrasound (HIFU)
KW - Immunomodulation
KW - Interventional oncology
KW - Temperature sensitive liposomes
KW - Thermal ablation
UR - http://www.scopus.com/inward/record.url?scp=85047182257&partnerID=8YFLogxK
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U2 - 10.1016/j.diii.2018.03.001
DO - 10.1016/j.diii.2018.03.001
M3 - Short survey
C2 - 29778401
AN - SCOPUS:85047182257
SN - 2211-5684
VL - 99
SP - 349
EP - 359
JO - Diagnostic and Interventional Imaging
JF - Diagnostic and Interventional Imaging
IS - 6
ER -