Human MettL3–MettL14 complex is a sequence-specific DNA adenine methyltransferase active on single-strand and unpaired DNA in vitro

Clayton B. Woodcock; Dan Yu; Taraneh Hajian; Jia Li; Yun Huang; Nan Dai; Ivan R. Corrêa; Tao Wu; Masoud Vedadi; Xing Zhang; Xiaodong Cheng

doi:10.1038/s41421-019-0136-4

Human MettL3–MettL14 complex is a sequence-specific DNA adenine methyltransferase active on single-strand and unpaired DNA in vitro

Clayton B. Woodcock, Dan Yu, Taraneh Hajian, Jia Li, Yun Huang, Nan Dai, Ivan R. Corrêa, Tao Wu, Masoud Vedadi, Xing Zhang, Xiaodong Cheng

Epigenetics & Molecular Carcinogenesis

Research output: Contribution to journal › Letter › peer-review

39 Scopus citations

Original language	English (US)
Article number	63
Journal	Cell Discovery
Volume	5
Issue number	1
DOIs	https://doi.org/10.1038/s41421-019-0136-4
State	Published - Dec 1 2019

ASJC Scopus subject areas

Biochemistry
Molecular Biology
Genetics
Cell Biology

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10.1038/s41421-019-0136-4

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@article{e632c336ab86426ab9815e3c03b7e186,

title = "Human MettL3–MettL14 complex is a sequence-specific DNA adenine methyltransferase active on single-strand and unpaired DNA in vitro",

author = "Woodcock, {Clayton B.} and Dan Yu and Taraneh Hajian and Jia Li and Yun Huang and Nan Dai and Corr{\^e}a, {Ivan R.} and Tao Wu and Masoud Vedadi and Xing Zhang and Xiaodong Cheng",

note = "Funding Information: We thank Dr. Robert M. Blumenthal of the University of Toledo College of Medicine for comments on the manuscript, Dr. Chuan He of the University of Chicago for the original MettL3 and MettL14 clones, and Dr. Cheryl Arrowsmith of Structural Genomics consortium for encouragement. This work is supported by grants from NIH (GM049245) and CPRIT (RR160029). Y.H. and J.L. is supported by NIH (R01HL134780 and R01HL146852) and the American Cancer Society (RSG-18-043-01-LIB). T.W. is supported by CPRIT (RR180072).",

year = "2019",

month = dec,

day = "1",

doi = "10.1038/s41421-019-0136-4",

language = "English (US)",

volume = "5",

journal = "Cell Discovery",

issn = "2056-5968",

publisher = "Nature Publishing Group",

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TY - JOUR

T1 - Human MettL3–MettL14 complex is a sequence-specific DNA adenine methyltransferase active on single-strand and unpaired DNA in vitro

AU - Woodcock, Clayton B.

AU - Yu, Dan

AU - Hajian, Taraneh

AU - Li, Jia

AU - Huang, Yun

AU - Dai, Nan

AU - Corrêa, Ivan R.

AU - Wu, Tao

AU - Vedadi, Masoud

AU - Zhang, Xing

AU - Cheng, Xiaodong

N1 - Funding Information: We thank Dr. Robert M. Blumenthal of the University of Toledo College of Medicine for comments on the manuscript, Dr. Chuan He of the University of Chicago for the original MettL3 and MettL14 clones, and Dr. Cheryl Arrowsmith of Structural Genomics consortium for encouragement. This work is supported by grants from NIH (GM049245) and CPRIT (RR160029). Y.H. and J.L. is supported by NIH (R01HL134780 and R01HL146852) and the American Cancer Society (RSG-18-043-01-LIB). T.W. is supported by CPRIT (RR180072).

PY - 2019/12/1

Y1 - 2019/12/1

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UR - http://www.scopus.com/inward/citedby.url?scp=85077050262&partnerID=8YFLogxK

U2 - 10.1038/s41421-019-0136-4

DO - 10.1038/s41421-019-0136-4

M3 - Letter

C2 - 31885874

AN - SCOPUS:85077050262

SN - 2056-5968

VL - 5

JO - Cell Discovery

JF - Cell Discovery

IS - 1

M1 - 63

ER -

Human MettL3–MettL14 complex is a sequence-specific DNA adenine methyltransferase active on single-strand and unpaired DNA in vitro

ASJC Scopus subject areas

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