Abstract
Aggressive digital papillary adenocarcinoma (ADPA) is a rare tumor that is considered to arise from eccrine sweat glands of the skin. It occurs predominantly in men with a mean age in the sixth decade. It shows a strong tendency for local recurrence and has the potential to metastasize to distant sites. Prompt diagnosis and regular follow-up are important to ensure the best possible outcome. We discuss a case of recurrent ADPA associated with subsequent squamous cell carcinoma (SCC) in different contralateral digits in a 55-year-old man. One SCC lesion tested positive for human papillomavirus (HPV)-58. HPV-associated digital SCCs have been reported; most cases are HPV-16 positive. This report describes a rare case of an HPV-58-positive invasive digital SCC and an HPV-73-positive SCC in situ associated with ADPA.
Original language | English (US) |
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Pages (from-to) | 375-378 |
Number of pages | 4 |
Journal | American Journal of Dermatopathology |
Volume | 31 |
Issue number | 4 |
DOIs | |
State | Published - Jun 2009 |
Externally published | Yes |
Keywords
- Aggressive digital papillary adenocarcinoma
- Digital squamous cell carcinoma
- Human papillomavirus-58
- Human papillomavirus-73
ASJC Scopus subject areas
- Pathology and Forensic Medicine
- Dermatology