Abstract
Zygomycosis is a rare but emerging mycosis. Because of the sub-optimal efficacy of the standard antifungal treatment for this disease, hyperbaric oxygen (HBO) has been used occasionally as an adjunctive therapeutic modality. A review of 28 published cases of zygomycosis indicates that adjunctive HBO may be beneficial in diabetic patients (94% survival), whereas its benefit in the small group of patients with haematological malignancies or bone marrow transplants is doubtful (33% survival; p 0.02). Prolonged courses of HBO were associated with a higher survival (100% survival; p 0.003). Additional studies are required to assess the optimal timing and dose for HBO treatment.
Original language | English (US) |
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Pages (from-to) | 515-517 |
Number of pages | 3 |
Journal | Clinical Microbiology and Infection |
Volume | 11 |
Issue number | 7 |
DOIs | |
State | Published - Jul 2005 |
Keywords
- Antifungal therapy
- Hyperbaric oxygen
- Immunocompromised patients
- Mucorales
- Zygomycosis
ASJC Scopus subject areas
- Microbiology (medical)
- Infectious Diseases