Hypersplenism due to disseminated candidiasis in a patient with acute leukemia

Gerald P. Bodey; David Dejongh; Adolfo Isassi; Emil J. Freireich

doi:10.1002/1097-0142(196908)24:2<417::AID-CNCR2820240226>3.0.CO;2-2

Hypersplenism due to disseminated candidiasis in a patient with acute leukemia

Gerald P. Bodey, David Dejongh, Adolfo Isassi, Emil J. Freireich

Leukemia

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24 Scopus citations

Abstract

A patient with acute myelogenous leukemia achieved a bone marrow remission with arabinosylcytosine therapy, but his peripheral blood counts failed to return to normal. Platelet survival studies confirmed the clinical diagnosis of hypersplenism, which was due to disseminated candidiasis. Following splenectomy, his peripheral blood returned to normal, and his disseminated candidiasis was cured with amphotericin B therapy.

Original language	English (US)
Pages (from-to)	417-420
Number of pages	4
Journal	Cancer
Volume	24
Issue number	2
DOIs	https://doi.org/10.1002/1097-0142(196908)24:2<417::AID-CNCR2820240226>3.0.CO;2-2
State	Published - Aug 1969

ASJC Scopus subject areas

Oncology
Cancer Research

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10.1002/1097-0142(196908)24:2<417::AID-CNCR2820240226>3.0.CO;2-2

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abstract = "A patient with acute myelogenous leukemia achieved a bone marrow remission with arabinosylcytosine therapy, but his peripheral blood counts failed to return to normal. Platelet survival studies confirmed the clinical diagnosis of hypersplenism, which was due to disseminated candidiasis. Following splenectomy, his peripheral blood returned to normal, and his disseminated candidiasis was cured with amphotericin B therapy.",

author = "Bodey, {Gerald P.} and David Dejongh and Adolfo Isassi and Freireich, {Emil J.}",

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AU - Isassi, Adolfo

AU - Freireich, Emil J.

PY - 1969/8

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N2 - A patient with acute myelogenous leukemia achieved a bone marrow remission with arabinosylcytosine therapy, but his peripheral blood counts failed to return to normal. Platelet survival studies confirmed the clinical diagnosis of hypersplenism, which was due to disseminated candidiasis. Following splenectomy, his peripheral blood returned to normal, and his disseminated candidiasis was cured with amphotericin B therapy.

AB - A patient with acute myelogenous leukemia achieved a bone marrow remission with arabinosylcytosine therapy, but his peripheral blood counts failed to return to normal. Platelet survival studies confirmed the clinical diagnosis of hypersplenism, which was due to disseminated candidiasis. Following splenectomy, his peripheral blood returned to normal, and his disseminated candidiasis was cured with amphotericin B therapy.

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Hypersplenism due to disseminated candidiasis in a patient with acute leukemia

Abstract

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