Identification of Sars-Cov-2 related volatile organic compounds from face masks

Hale Secilmis Canbay; Gorkem Kismali; Fatih Mehmet Emen; Arif Dogan Habiloglu; Baris Sareyyupoglu; Aytac Akcay; Hakan Ozturk; Merve Alpay; Durmus Atilgan; Begum Saral; Bulent Bas; Nevin Ince; Sevim Isparta; Idris Sahin; Aykut Ozkul; Yasemin Salgirli Demirbas

doi:10.1016/j.microc.2023.109756

Identification of Sars-Cov-2 related volatile organic compounds from face masks

Hale Secilmis Canbay
, Gorkem Kismali
, Fatih Mehmet Emen
, Arif Dogan Habiloglu
, Baris Sareyyupoglu
, Aytac Akcay
, Hakan Ozturk
, Merve Alpay
, Durmus Atilgan
, Begum Saral
, Bulent Bas
, Nevin Ince
, Sevim Isparta
, Idris Sahin
, Aykut Ozkul
, Yasemin Salgirli Demirbas

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

This study aims to identify SARS-CoV-2-related volatile organic compounds (VOCs) of the exhaled breath from face masks. Face masks collected from SARS-CoV-2 patients (n = 30) and the control group (n = 11) were analyzed to detect VOCs in the exhaled breath using the Headspace-Gas Chromatography Mass Spectrometry. Significant increases in concentrations of toluene, hexadecane, and phenol were detected in the face masks belonging to patient groups (p < 0.001). Clinical significance was further found in isobutyric acid levels considering Cohen's d value (p = 0.070). The findings of this study suggest that monitoring toluene, hexadecane, phenol, and isobutyric acid could provide considerable support in rapid screening of SARS-CoV-2.

Original language	English (US)
Article number	109756
Journal	Microchemical Journal
Volume	197
DOIs	https://doi.org/10.1016/j.microc.2023.109756
State	Published - Feb 2024
Externally published	Yes

ASJC Scopus subject areas

Analytical Chemistry
Spectroscopy

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10.1016/j.microc.2023.109756

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Canbay, H. S., Kismali, G., Emen, F. M., Habiloglu, A. D., Sareyyupoglu, B., Akcay, A., Ozturk, H., Alpay, M., Atilgan, D., Saral, B., Bas, B., Ince, N., Isparta, S., Sahin, I., Ozkul, A., & Demirbas, Y. S. (2024). Identification of Sars-Cov-2 related volatile organic compounds from face masks. Microchemical Journal, 197, Article 109756. https://doi.org/10.1016/j.microc.2023.109756

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title = "Identification of Sars-Cov-2 related volatile organic compounds from face masks",

abstract = "This study aims to identify SARS-CoV-2-related volatile organic compounds (VOCs) of the exhaled breath from face masks. Face masks collected from SARS-CoV-2 patients (n = 30) and the control group (n = 11) were analyzed to detect VOCs in the exhaled breath using the Headspace-Gas Chromatography Mass Spectrometry. Significant increases in concentrations of toluene, hexadecane, and phenol were detected in the face masks belonging to patient groups (p < 0.001). Clinical significance was further found in isobutyric acid levels considering Cohen's d value (p = 0.070). The findings of this study suggest that monitoring toluene, hexadecane, phenol, and isobutyric acid could provide considerable support in rapid screening of SARS-CoV-2.",

author = "Canbay, \{Hale Secilmis\} and Gorkem Kismali and Emen, \{Fatih Mehmet\} and Habiloglu, \{Arif Dogan\} and Baris Sareyyupoglu and Aytac Akcay and Hakan Ozturk and Merve Alpay and Durmus Atilgan and Begum Saral and Bulent Bas and Nevin Ince and Sevim Isparta and Idris Sahin and Aykut Ozkul and Demirbas, \{Yasemin Salgirli\}",

note = "Publisher Copyright: {\textcopyright} 2023 Elsevier B.V.",

year = "2024",

month = feb,

doi = "10.1016/j.microc.2023.109756",

language = "English (US)",

volume = "197",

journal = "Microchemical Journal",

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T1 - Identification of Sars-Cov-2 related volatile organic compounds from face masks

AU - Canbay, Hale Secilmis

AU - Kismali, Gorkem

AU - Emen, Fatih Mehmet

AU - Habiloglu, Arif Dogan

AU - Sareyyupoglu, Baris

AU - Akcay, Aytac

AU - Ozturk, Hakan

AU - Alpay, Merve

AU - Atilgan, Durmus

AU - Saral, Begum

AU - Bas, Bulent

AU - Ince, Nevin

AU - Isparta, Sevim

AU - Sahin, Idris

AU - Ozkul, Aykut

AU - Demirbas, Yasemin Salgirli

PY - 2024/2

Y1 - 2024/2

N2 - This study aims to identify SARS-CoV-2-related volatile organic compounds (VOCs) of the exhaled breath from face masks. Face masks collected from SARS-CoV-2 patients (n = 30) and the control group (n = 11) were analyzed to detect VOCs in the exhaled breath using the Headspace-Gas Chromatography Mass Spectrometry. Significant increases in concentrations of toluene, hexadecane, and phenol were detected in the face masks belonging to patient groups (p < 0.001). Clinical significance was further found in isobutyric acid levels considering Cohen's d value (p = 0.070). The findings of this study suggest that monitoring toluene, hexadecane, phenol, and isobutyric acid could provide considerable support in rapid screening of SARS-CoV-2.

AB - This study aims to identify SARS-CoV-2-related volatile organic compounds (VOCs) of the exhaled breath from face masks. Face masks collected from SARS-CoV-2 patients (n = 30) and the control group (n = 11) were analyzed to detect VOCs in the exhaled breath using the Headspace-Gas Chromatography Mass Spectrometry. Significant increases in concentrations of toluene, hexadecane, and phenol were detected in the face masks belonging to patient groups (p < 0.001). Clinical significance was further found in isobutyric acid levels considering Cohen's d value (p = 0.070). The findings of this study suggest that monitoring toluene, hexadecane, phenol, and isobutyric acid could provide considerable support in rapid screening of SARS-CoV-2.

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U2 - 10.1016/j.microc.2023.109756

DO - 10.1016/j.microc.2023.109756

M3 - Article

AN - SCOPUS:85180113727

SN - 0026-265X

VL - 197

JO - Microchemical Journal

JF - Microchemical Journal

M1 - 109756

ER -

Identification of Sars-Cov-2 related volatile organic compounds from face masks

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