TY - JOUR
T1 - Identifying Gaps in Research on Rehabilitation for Patients With Head and Neck Cancer
T2 - A Scoping Review
AU - Parke, Sara C.
AU - Oza, Sonal
AU - Shahpar, Sam
AU - Ngo-Huang, An
AU - Herbert, Aliea
AU - Barksdale, Touré
AU - Gerber, Lynn
N1 - Funding Information:
Supported by the National Center for Advancing Translational Sciences of the National Institutes of Health (award no. UL1 TR002319) for REDCap use through the Institute of Translational Health Sciences.
Funding Information:
Supported by the National Center for Advancing Translational Sciences of the National Institutes of Health (award no. UL1 TR002319) for REDCap use through the Institute of Translational Health Sciences. The authors would like to thank Andrea Ball, MLS, MSIM, research librarian at the University of Washington, for her assistance with development of the original search strategy. The authors would also like to thank Sunita Patterson, BA, at the University of Texas MD Anderson Cancer Center for her editorial assistance.
Publisher Copyright:
© 2019 American Congress of Rehabilitation Medicine
PY - 2019/12
Y1 - 2019/12
N2 - Objectives: Examine the amount and nature of research activity in head and neck cancer (HNC) rehabilitation; highlight publication trends, including information about the authors, settings, and study designs; and identify gaps in the existing literature. Data Sources: Eligible studies were identified using PubMed, Embase, and CINAHL databases. Study Selection: Inclusion criteria included human subjects, English language, publication between 1/1/1990 and 4/30/2017, HNC patients at any timepoint in disease, and evaluation of rehabilitation outcomes as described by the International Classification of Functioning, Disability and Health (ICF) framework. Exclusion criteria included intervention or outcome not specific to rehabilitation or the HNC population, and protocols or abstracts without corresponding full manuscripts. Data Extraction: An established 6-step scoping review framework was utilized to develop the review protocol. A 3-level review was then performed. Data on eligible studies were collected using a Research Electronic Data Capture (REDCap) tool. Data Synthesis: Among 2201 publications, 258 met inclusion criteria. Publication rate increased by 390% over the study timeframe. Most studies were observational (n=150). Few were interventional (n=35). The most common interventions focused on chewing or swallowing (n=14), followed by exercise (n=10). Most primary outcome measures fit the ICF definition of impairment; fewer fit the definitions of activity limitation or participation restriction. Conclusions: Although research volume in HNC rehabilitation is increasing, the literature is dominated by small (≤100 patients), outpatient-based observational studies involving chewing or swallowing-related impairments. More prospective studies in multidisciplinary domains across the cancer care continuum are needed. There is particular need for interventional studies and prospective observational studies. Future studies should evaluate clinically-relevant activity limitations and participation restrictions. Rehabilitation professionals have an important role in the design of future HNC rehabilitation research.
AB - Objectives: Examine the amount and nature of research activity in head and neck cancer (HNC) rehabilitation; highlight publication trends, including information about the authors, settings, and study designs; and identify gaps in the existing literature. Data Sources: Eligible studies were identified using PubMed, Embase, and CINAHL databases. Study Selection: Inclusion criteria included human subjects, English language, publication between 1/1/1990 and 4/30/2017, HNC patients at any timepoint in disease, and evaluation of rehabilitation outcomes as described by the International Classification of Functioning, Disability and Health (ICF) framework. Exclusion criteria included intervention or outcome not specific to rehabilitation or the HNC population, and protocols or abstracts without corresponding full manuscripts. Data Extraction: An established 6-step scoping review framework was utilized to develop the review protocol. A 3-level review was then performed. Data on eligible studies were collected using a Research Electronic Data Capture (REDCap) tool. Data Synthesis: Among 2201 publications, 258 met inclusion criteria. Publication rate increased by 390% over the study timeframe. Most studies were observational (n=150). Few were interventional (n=35). The most common interventions focused on chewing or swallowing (n=14), followed by exercise (n=10). Most primary outcome measures fit the ICF definition of impairment; fewer fit the definitions of activity limitation or participation restriction. Conclusions: Although research volume in HNC rehabilitation is increasing, the literature is dominated by small (≤100 patients), outpatient-based observational studies involving chewing or swallowing-related impairments. More prospective studies in multidisciplinary domains across the cancer care continuum are needed. There is particular need for interventional studies and prospective observational studies. Future studies should evaluate clinically-relevant activity limitations and participation restrictions. Rehabilitation professionals have an important role in the design of future HNC rehabilitation research.
KW - Cancer
KW - Head
KW - Neck
KW - Neoplasm
KW - Rehabilitation
UR - http://www.scopus.com/inward/record.url?scp=85066943372&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85066943372&partnerID=8YFLogxK
U2 - 10.1016/j.apmr.2019.03.022
DO - 10.1016/j.apmr.2019.03.022
M3 - Review article
C2 - 31082380
AN - SCOPUS:85066943372
SN - 0003-9993
VL - 100
SP - 2381
EP - 2388
JO - Archives of Physical Medicine and Rehabilitation
JF - Archives of Physical Medicine and Rehabilitation
IS - 12
ER -