Identifying possible outcome domains from existing outcome measures to inform an OMERACT core domain set for safety in rheumatology trials

Louise Klokker; Dorthe B. Berthelsen; Thasia Woodworth; Kathleen M. Andersen; Daniel E. Furst; Dan Devoe; Paula R. Williamson; Maria E. Suarez-Almazor; Vibeke Strand; Amye L. Leong; Niti Goel; Maarten Boers; Peter M. Brooks; Lyn March; Victor S. Sloan; Peter Tugwell; Lee S. Simon; Robin Christensen

doi:10.3899/jrheum.190196

Identifying possible outcome domains from existing outcome measures to inform an OMERACT core domain set for safety in rheumatology trials

Louise Klokker, Dorthe B. Berthelsen, Thasia Woodworth, Kathleen M. Andersen, Daniel E. Furst, Dan Devoe, Paula R. Williamson, Maria E. Suarez-Almazor, Vibeke Strand, Amye L. Leong, Niti Goel, Maarten Boers, Peter M. Brooks, Lyn March, Victor S. Sloan, Peter Tugwell, Lee S. Simon, Robin Christensen

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

Objective. The Outcome Measures in Rheumatology (OMERACT) Safety Working Group objective was to identify harm domains from existing outcome measurements in rheumatology. Methods. Systematically searching the MEDLINE database on January 24, 2017, we identified full-text articles that could be used for harm outcomes in rheumatology. Domains/items from the identified instruments were described and the content synthesized to provide a preliminary framework for harm outcomes. Results. From 435 possible references, 24 were read in full text and 9 were included: 7 measurement instruments were identified. Investigation of domains/items revealed considerable heterogeneity in the grouping and approach. Conclusion. The ideal way to assess harm aspects from the patients' perspective has not yet been ascertained.

Original language	English (US)
Pages (from-to)	1173-1178
Number of pages	6
Journal	Journal of Rheumatology
Volume	46
Issue number	9
DOIs	https://doi.org/10.3899/jrheum.190196
State	Published - Sep 1 2019

Keywords

Adverse events
Arthritis
Core outcome set
Harm
OMERACT
Safety

ASJC Scopus subject areas

Rheumatology
Immunology and Allergy
Immunology

Access to Document

10.3899/jrheum.190196

Cite this

Klokker, L., Berthelsen, D. B., Woodworth, T., Andersen, K. M., Furst, D. E., Devoe, D., Williamson, P. R., Suarez-Almazor, M. E., Strand, V., Leong, A. L., Goel, N., Boers, M., Brooks, P. M., March, L., Sloan, V. S., Tugwell, P., Simon, L. S., & Christensen, R. (2019). Identifying possible outcome domains from existing outcome measures to inform an OMERACT core domain set for safety in rheumatology trials. Journal of Rheumatology, 46(9), 1173-1178. https://doi.org/10.3899/jrheum.190196

Klokker, L, Berthelsen, DB, Woodworth, T, Andersen, KM, Furst, DE, Devoe, D, Williamson, PR, Suarez-Almazor, ME, Strand, V, Leong, AL, Goel, N, Boers, M, Brooks, PM, March, L, Sloan, VS, Tugwell, P, Simon, LS & Christensen, R 2019, 'Identifying possible outcome domains from existing outcome measures to inform an OMERACT core domain set for safety in rheumatology trials', Journal of Rheumatology, vol. 46, no. 9, pp. 1173-1178. https://doi.org/10.3899/jrheum.190196

@article{56a1959bf72149a894a1bed1b1d6c9bb,

title = "Identifying possible outcome domains from existing outcome measures to inform an OMERACT core domain set for safety in rheumatology trials",

abstract = "Objective. The Outcome Measures in Rheumatology (OMERACT) Safety Working Group objective was to identify harm domains from existing outcome measurements in rheumatology. Methods. Systematically searching the MEDLINE database on January 24, 2017, we identified full-text articles that could be used for harm outcomes in rheumatology. Domains/items from the identified instruments were described and the content synthesized to provide a preliminary framework for harm outcomes. Results. From 435 possible references, 24 were read in full text and 9 were included: 7 measurement instruments were identified. Investigation of domains/items revealed considerable heterogeneity in the grouping and approach. Conclusion. The ideal way to assess harm aspects from the patients' perspective has not yet been ascertained.",

keywords = "Adverse events, Arthritis, Core outcome set, Harm, OMERACT, Safety",

author = "Louise Klokker and Berthelsen, {Dorthe B.} and Thasia Woodworth and Andersen, {Kathleen M.} and Furst, {Daniel E.} and Dan Devoe and Williamson, {Paula R.} and Suarez-Almazor, {Maria E.} and Vibeke Strand and Leong, {Amye L.} and Niti Goel and Maarten Boers and Brooks, {Peter M.} and Lyn March and Sloan, {Victor S.} and Peter Tugwell and Simon, {Lee S.} and Robin Christensen",

year = "2019",

month = sep,

day = "1",

doi = "10.3899/jrheum.190196",

language = "English (US)",

volume = "46",

pages = "1173--1178",

journal = "Journal of Rheumatology",

issn = "0315-162X",

publisher = "Journal of Rheumatology",

number = "9",

}

TY - JOUR

T1 - Identifying possible outcome domains from existing outcome measures to inform an OMERACT core domain set for safety in rheumatology trials

AU - Klokker, Louise

AU - Berthelsen, Dorthe B.

AU - Woodworth, Thasia

AU - Andersen, Kathleen M.

AU - Furst, Daniel E.

AU - Devoe, Dan

AU - Williamson, Paula R.

AU - Suarez-Almazor, Maria E.

AU - Strand, Vibeke

AU - Leong, Amye L.

AU - Goel, Niti

AU - Boers, Maarten

AU - Brooks, Peter M.

AU - March, Lyn

AU - Sloan, Victor S.

AU - Tugwell, Peter

AU - Simon, Lee S.

AU - Christensen, Robin

PY - 2019/9/1

Y1 - 2019/9/1

N2 - Objective. The Outcome Measures in Rheumatology (OMERACT) Safety Working Group objective was to identify harm domains from existing outcome measurements in rheumatology. Methods. Systematically searching the MEDLINE database on January 24, 2017, we identified full-text articles that could be used for harm outcomes in rheumatology. Domains/items from the identified instruments were described and the content synthesized to provide a preliminary framework for harm outcomes. Results. From 435 possible references, 24 were read in full text and 9 were included: 7 measurement instruments were identified. Investigation of domains/items revealed considerable heterogeneity in the grouping and approach. Conclusion. The ideal way to assess harm aspects from the patients' perspective has not yet been ascertained.

AB - Objective. The Outcome Measures in Rheumatology (OMERACT) Safety Working Group objective was to identify harm domains from existing outcome measurements in rheumatology. Methods. Systematically searching the MEDLINE database on January 24, 2017, we identified full-text articles that could be used for harm outcomes in rheumatology. Domains/items from the identified instruments were described and the content synthesized to provide a preliminary framework for harm outcomes. Results. From 435 possible references, 24 were read in full text and 9 were included: 7 measurement instruments were identified. Investigation of domains/items revealed considerable heterogeneity in the grouping and approach. Conclusion. The ideal way to assess harm aspects from the patients' perspective has not yet been ascertained.

KW - Adverse events

KW - Arthritis

KW - Core outcome set

KW - Harm

KW - OMERACT

KW - Safety

UR - http://www.scopus.com/inward/record.url?scp=85071720701&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85071720701&partnerID=8YFLogxK

U2 - 10.3899/jrheum.190196

DO - 10.3899/jrheum.190196

M3 - Article

C2 - 31043547

AN - SCOPUS:85071720701

SN - 0315-162X

VL - 46

SP - 1173

EP - 1178

JO - Journal of Rheumatology

JF - Journal of Rheumatology

IS - 9

ER -

Identifying possible outcome domains from existing outcome measures to inform an OMERACT core domain set for safety in rheumatology trials

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this