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Idiopathic thrombocytopenic purpura following successful treatment of acute lymphoblastic leukemia

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Abstract

Thrombocytopenia is common in patients with acute lymphocytic leukemia (ALL) at diagnosis. It is a universal side effect of dose-intensive regimens employed in the treatment of adult ALL. In patients with ALL who achieve remission, thrombocytopenia frequently indicates relapse. We report three adult patients successfully treated for ALL who developed thrombocytopenia and were found to have immune-mediated thrombocytopenia (ITP). Possible pathophysiologic mechanisms underlying the association of ALL and ITP are discussed.

Original languageEnglish (US)
Pages (from-to)217-220
Number of pages4
JournalLeukemia and Lymphoma
Volume41
Issue number1-2
DOIs
StatePublished - 2001

Keywords

  • ALL
  • ITP
  • Leukemia
  • Thrombocytopenia

ASJC Scopus subject areas

  • Hematology
  • Oncology
  • Cancer Research

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