Immunoglobulin G4-positive sclerosing idiopathic orbital Inflammation: New Neuro-ophthalmological Presentations

Nagham Al-Zubidi; Hidehiro Oku; Elizabeth Verner-Cole; Kanako Yamada; Patricia Chevez-Barrios; Masahiro Tonari; Takuji Kurimoto; Motomu Tsuji; Tsunehiko Ikeda; Andrew G. Lee

doi:10.3109/01658107.2012.752853

Immunoglobulin G4-positive sclerosing idiopathic orbital Inflammation: New Neuro-ophthalmological Presentations

Nagham Al-Zubidi, Hidehiro Oku, Elizabeth Verner-Cole, Kanako Yamada, Patricia Chevez-Barrios, Masahiro Tonari, Takuji Kurimoto, Motomu Tsuji, Tsunehiko Ikeda, Andrew G. Lee

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

We report two rare cases of biopsy proven Immunoglobulin G4-related sclerosing orbital inflammation (IgG4SOI). The first case had intracranial involvement which, to our knowledge, is the first IgG4SOI case with serum cerebrospinal fluid abnormalities and the second case had an unusual presentation of a compressive optic neuropathy and systemic lymphadenopathy.

Original language	English (US)
Pages (from-to)	24-30
Number of pages	7
Journal	Neuro-Ophthalmology
Volume	37
Issue number	1
DOIs	https://doi.org/10.3109/01658107.2012.752853
State	Published - Feb 8 2013

Keywords

Compressive optic neuropathy
IgG4
Immunoglobulin G4-positive sclerosing idiopathic orbital inflammation
Immunoglobulin G4-positive with intracranial involvement
Sclerosing idiopathic orbital inflammation
Systemic lymphadenopathy

ASJC Scopus subject areas

Ophthalmology
Clinical Neurology

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10.3109/01658107.2012.752853

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title = "Immunoglobulin G4-positive sclerosing idiopathic orbital Inflammation: New Neuro-ophthalmological Presentations",

abstract = "We report two rare cases of biopsy proven Immunoglobulin G4-related sclerosing orbital inflammation (IgG4SOI). The first case had intracranial involvement which, to our knowledge, is the first IgG4SOI case with serum cerebrospinal fluid abnormalities and the second case had an unusual presentation of a compressive optic neuropathy and systemic lymphadenopathy.",

keywords = "Compressive optic neuropathy, IgG4, Immunoglobulin G4-positive sclerosing idiopathic orbital inflammation, Immunoglobulin G4-positive with intracranial involvement, Sclerosing idiopathic orbital inflammation, Systemic lymphadenopathy",

author = "Nagham Al-Zubidi and Hidehiro Oku and Elizabeth Verner-Cole and Kanako Yamada and Patricia Chevez-Barrios and Masahiro Tonari and Takuji Kurimoto and Motomu Tsuji and Tsunehiko Ikeda and Lee, {Andrew G.}",

note = "Funding Information: Declaration of Interest: The authors report no conflicts of interest. The authors alone are responsible for the content and writing of the paper. This work was supported in part by an unrestricted grant from Research to Prevent Blindness, Inc. NY, NY. The authors have no conflicts of interest in this article to disclose.",

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doi = "10.3109/01658107.2012.752853",

language = "English (US)",

volume = "37",

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T2 - New Neuro-ophthalmological Presentations

AU - Al-Zubidi, Nagham

AU - Oku, Hidehiro

AU - Verner-Cole, Elizabeth

AU - Yamada, Kanako

AU - Chevez-Barrios, Patricia

AU - Tonari, Masahiro

AU - Kurimoto, Takuji

AU - Tsuji, Motomu

AU - Ikeda, Tsunehiko

AU - Lee, Andrew G.

N1 - Funding Information: Declaration of Interest: The authors report no conflicts of interest. The authors alone are responsible for the content and writing of the paper. This work was supported in part by an unrestricted grant from Research to Prevent Blindness, Inc. NY, NY. The authors have no conflicts of interest in this article to disclose.

PY - 2013/2/8

Y1 - 2013/2/8

N2 - We report two rare cases of biopsy proven Immunoglobulin G4-related sclerosing orbital inflammation (IgG4SOI). The first case had intracranial involvement which, to our knowledge, is the first IgG4SOI case with serum cerebrospinal fluid abnormalities and the second case had an unusual presentation of a compressive optic neuropathy and systemic lymphadenopathy.

AB - We report two rare cases of biopsy proven Immunoglobulin G4-related sclerosing orbital inflammation (IgG4SOI). The first case had intracranial involvement which, to our knowledge, is the first IgG4SOI case with serum cerebrospinal fluid abnormalities and the second case had an unusual presentation of a compressive optic neuropathy and systemic lymphadenopathy.

KW - Compressive optic neuropathy

KW - IgG4

KW - Immunoglobulin G4-positive sclerosing idiopathic orbital inflammation

KW - Immunoglobulin G4-positive with intracranial involvement

KW - Sclerosing idiopathic orbital inflammation

KW - Systemic lymphadenopathy

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Immunoglobulin G4-positive sclerosing idiopathic orbital Inflammation: New Neuro-ophthalmological Presentations

Abstract

Keywords

ASJC Scopus subject areas

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