Immunotherapy and Radiation

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Scopus citations

Abstract

Radiation is an essential tool in cancer therapy, both in the definitive and palliative setting. Radiation therapy can drive the cancer immune cycle via several mechanisms, but it also has immune suppressive effects that might be overcome via radiation/immunotherapy combination approaches. Understanding this underlying biology will lead to improved combination therapy approaches. Although clinical evidence of radiation and immunotherapy combination approaches in the metastatic setting to induce an abscopal response is limited, combination approaches in the oligometastatic and definitive setting are extremely promising.

Original languageEnglish (US)
Title of host publicationAdvances in Experimental Medicine and Biology
PublisherSpringer
Pages205-213
Number of pages9
DOIs
StatePublished - 2020

Publication series

NameAdvances in Experimental Medicine and Biology
Volume1244
ISSN (Print)0065-2598
ISSN (Electronic)2214-8019

Keywords

  • Abscopal response
  • Immunotherapy
  • Radiation
  • Radiotherapy

ASJC Scopus subject areas

  • General Biochemistry, Genetics and Molecular Biology

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