Impact of oral hygiene on head and neck cancer risk in a Chinese population

Daisuke Kawakita, Yuan Chin Amy Lee, Qian Li, Yuji Chen, Chien Jen Chen, Wan Lun Hsu, Pei Jen Lou, Cairong Zhu, Jian Pan, Hongbing Shen, Hongxia Ma, Lin Cai, Baochang He, Yu Wang, Xiaoyan Zhou, Qinghai Ji, Baosen Zhou, Wei Wu, Jie Ma, Paolo BoffettaZuo Feng Zhang, Min Dai, Mia Hashibe

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Background: Although the impact of oral hygiene on head and neck cancer risk has been investigated, few studies have been conducted among the Asian population. Methods: We conducted a multicenter case-control study to investigate this potential association. We performed unconditional multiple logistic regression models adjusted by potential confounders. Results: We observed an inverse association of frequency of dental visits with head and neck cancer risk, with an adjusted odds ratio (OR) of 3.70 (95% CI 2.51-5.45) for never dental visits compared with ≥1 time/year (Ptrend <.001). We also observed a positive association between the number of missing teeth and head and neck cancer risk, with an adjusted OR for ≥5 missing teeth compared with <5 missing teeth of 1.49 (95% CI 1.08-2.04). Combining multiple oral hygiene indicators, poor oral hygiene scores increased head and neck cancer risk. Conclusion: Poor oral hygiene may increase head and neck cancer risk in the Chinese population. Therefore, improving oral hygiene may contribute to reducing the head and neck cancer risk in the Chinese population.

Original languageEnglish (US)
Pages (from-to)2549-2557
Number of pages9
JournalHead and Neck
Volume39
Issue number12
DOIs
StatePublished - Dec 2017

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Oral Hygiene
Head and Neck Neoplasms
Tooth
Population
Logistic Models
Odds Ratio
Case-Control Studies

Keywords

  • Chinese
  • dental care
  • head and neck cancer
  • oral hygiene
  • risk

ASJC Scopus subject areas

  • Otorhinolaryngology

Cite this

Kawakita, D., Lee, Y. C. A., Li, Q., Chen, Y., Chen, C. J., Hsu, W. L., ... Hashibe, M. (2017). Impact of oral hygiene on head and neck cancer risk in a Chinese population. Head and Neck, 39(12), 2549-2557. https://doi.org/10.1002/hed.24929

Impact of oral hygiene on head and neck cancer risk in a Chinese population. / Kawakita, Daisuke; Lee, Yuan Chin Amy; Li, Qian; Chen, Yuji; Chen, Chien Jen; Hsu, Wan Lun; Lou, Pei Jen; Zhu, Cairong; Pan, Jian; Shen, Hongbing; Ma, Hongxia; Cai, Lin; He, Baochang; Wang, Yu; Zhou, Xiaoyan; Ji, Qinghai; Zhou, Baosen; Wu, Wei; Ma, Jie; Boffetta, Paolo; Zhang, Zuo Feng; Dai, Min; Hashibe, Mia.

In: Head and Neck, Vol. 39, No. 12, 12.2017, p. 2549-2557.

Research output: Contribution to journalArticle

Kawakita, D, Lee, YCA, Li, Q, Chen, Y, Chen, CJ, Hsu, WL, Lou, PJ, Zhu, C, Pan, J, Shen, H, Ma, H, Cai, L, He, B, Wang, Y, Zhou, X, Ji, Q, Zhou, B, Wu, W, Ma, J, Boffetta, P, Zhang, ZF, Dai, M & Hashibe, M 2017, 'Impact of oral hygiene on head and neck cancer risk in a Chinese population', Head and Neck, vol. 39, no. 12, pp. 2549-2557. https://doi.org/10.1002/hed.24929
Kawakita D, Lee YCA, Li Q, Chen Y, Chen CJ, Hsu WL et al. Impact of oral hygiene on head and neck cancer risk in a Chinese population. Head and Neck. 2017 Dec;39(12):2549-2557. https://doi.org/10.1002/hed.24929
Kawakita, Daisuke ; Lee, Yuan Chin Amy ; Li, Qian ; Chen, Yuji ; Chen, Chien Jen ; Hsu, Wan Lun ; Lou, Pei Jen ; Zhu, Cairong ; Pan, Jian ; Shen, Hongbing ; Ma, Hongxia ; Cai, Lin ; He, Baochang ; Wang, Yu ; Zhou, Xiaoyan ; Ji, Qinghai ; Zhou, Baosen ; Wu, Wei ; Ma, Jie ; Boffetta, Paolo ; Zhang, Zuo Feng ; Dai, Min ; Hashibe, Mia. / Impact of oral hygiene on head and neck cancer risk in a Chinese population. In: Head and Neck. 2017 ; Vol. 39, No. 12. pp. 2549-2557.
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AU - Lee, Yuan Chin Amy

AU - Li, Qian

AU - Chen, Yuji

AU - Chen, Chien Jen

AU - Hsu, Wan Lun

AU - Lou, Pei Jen

AU - Zhu, Cairong

AU - Pan, Jian

AU - Shen, Hongbing

AU - Ma, Hongxia

AU - Cai, Lin

AU - He, Baochang

AU - Wang, Yu

AU - Zhou, Xiaoyan

AU - Ji, Qinghai

AU - Zhou, Baosen

AU - Wu, Wei

AU - Ma, Jie

AU - Boffetta, Paolo

AU - Zhang, Zuo Feng

AU - Dai, Min

AU - Hashibe, Mia

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AB - Background: Although the impact of oral hygiene on head and neck cancer risk has been investigated, few studies have been conducted among the Asian population. Methods: We conducted a multicenter case-control study to investigate this potential association. We performed unconditional multiple logistic regression models adjusted by potential confounders. Results: We observed an inverse association of frequency of dental visits with head and neck cancer risk, with an adjusted odds ratio (OR) of 3.70 (95% CI 2.51-5.45) for never dental visits compared with ≥1 time/year (Ptrend <.001). We also observed a positive association between the number of missing teeth and head and neck cancer risk, with an adjusted OR for ≥5 missing teeth compared with <5 missing teeth of 1.49 (95% CI 1.08-2.04). Combining multiple oral hygiene indicators, poor oral hygiene scores increased head and neck cancer risk. Conclusion: Poor oral hygiene may increase head and neck cancer risk in the Chinese population. Therefore, improving oral hygiene may contribute to reducing the head and neck cancer risk in the Chinese population.

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