Impairment of human sperm motility and viability by quercetin is independent of lipid peroxidation

K. L. Khanduja, A. Verma, A. Bhardwaj

Research output: Contribution to journalArticlepeer-review

47 Scopus citations

Abstract

Human sperm motility, viability and lipid peroxidation were assessed in Ringer-Tyrode supplemented with different concentrations of quercetin. An irreversible and dose-dependent fall in sperm motility was observed with quercetin (5-200 μM). However, sperm viability was decreased only at higher concentrations (50-100 μM) of quercetin. This inhibition in sperm motility and viability has been linked with decreased Ca2+-ATPase activity, as there was no effect of quercetin on sperm lipid peroxidation.

Original languageEnglish (US)
Pages (from-to)277-281
Number of pages5
JournalAndrologia
Volume33
Issue number5
DOIs
StatePublished - 2001
Externally publishedYes

Keywords

  • ATPase
  • Ca
  • Lipid peroxidation
  • Quercetin
  • Sperm motility
  • Viability

ASJC Scopus subject areas

  • Endocrinology
  • Urology

Fingerprint

Dive into the research topics of 'Impairment of human sperm motility and viability by quercetin is independent of lipid peroxidation'. Together they form a unique fingerprint.

Cite this