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In vitro activity of paldimycin (U-70138F) against gram-positive bacteria isolated from patients with cancer

  • K. V.I. Rolston
  • , B. LeBlanc
  • , D. H. Ho
  • , G. P. Bodey

Research output: Contribution to journalArticlepeer-review

Abstract

The in vitro activity of paldimycin, a novel antimicrobial agent, was compared with that of vancomycin against 306 gram-positive isolates (representing 12 bacterial species) obtained from patients with cancer. Paldimycin had lower MICs for 90% of isolates than vancomycin did against most isolates tested. Its activity however, was medium and pH dependent, being greatest in Nutrient broth at a pH of 6.8.

Original languageEnglish (US)
Pages (from-to)650-652
Number of pages3
JournalAntimicrobial agents and chemotherapy
Volume31
Issue number4
DOIs
StatePublished - 1987

ASJC Scopus subject areas

  • Pharmacology
  • Pharmacology (medical)
  • Infectious Diseases

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