In vivo activity of tumor necrosis factor (TNF) mutants: Secretory but not membrane-bound TNF mediates the regression of retrovirally transduced murine tumor

Keyphrases

• Tumor Necrosis Factor-α 100%
• Murine Tumors 100%
• In Vivo Activity 100%
• Membrane-bound 100%
• Tumor 47%
• Tumor Cells 23%
• Retrovirus 17%
• Complementary DNA (cDNA) 11%
• Human Tumors 11%
• Tumor Regression 11%
• Supernatant 5%
• Tumor Growth 5%
• Lysis 5%
• Tumor Model 5%
• Membrane-associated 5%
• Transmembrane Domain 5%
• Cell Surface 5%
• Murine Fibrosarcoma 5%
• Retroviral Vector 5%
• L929 5%
• Immunodeficient Mice 5%
• Retroviral Transduction 5%
• T-cell Mediated 5%
• Syngeneic Mice 5%
• In Vivo Injection 5%
• Host Response 5%
• L929 Cells 5%
• Animal-free 5%
• Anti-tumor Necrosis Factor Antibody 5%
• Direct Lysis 5%
• Tumor Necrosis Factor Gene 5%
• Second Tumor 5%
• Repeated Experiments 5%

Immunology and Microbiology

• Tumor Necrosis Factor 100%
• Tumor Cell 22%
• Retrovirus 16%
• T Cell 5%
• Supernatant 5%
• Wild Type 5%
• Immune Response 5%
• Syngenic 5%
• Cell Surface 5%
• Secretion (Process) 5%
• Retrovirus Vector 5%
• Tumor Necrosis Factor Antibody 5%
• In Vitro 5%