Inflammatory Arthritis Post Immune Checkpoint Inhibitor Therapy

Savannah Bowman; Rodabe N. Amaria; Huifang Lu

doi:10.1007/978-3-031-83533-9_52

Inflammatory Arthritis Post Immune Checkpoint Inhibitor Therapy

Savannah Bowman
, Rodabe N. Amaria
, Huifang Lu

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

This is a case of a patients with T4N0 sinonasal malignant melanoma who had received two cycles of ipilimumab and nivolumab who subsequently developed inflammatory arthritis of bilateral knees related to ICI treatment. This patient received corticosteroids and sulfasalazine with no response, but achieved complete remission on tocilizumab. This therapeutic effect sustained over 2 years despite patient resumed nivolumab monotherapy for cancer recurrence while receiving tocilizumab as concurrent treatment.

Original language	English (US)
Title of host publication	Challenging Cases in Immunotherapy Related Organ Toxicities
Publisher	Springer Science+Business Media
Pages	417-423
Number of pages	7
ISBN (Electronic)	9783031835339
ISBN (Print)	9783031835322
DOIs	https://doi.org/10.1007/978-3-031-83533-9_52
State	Published - Jan 1 2025

Keywords

Arthritis
Immune checkpoint inhibitors
Immune related adverse event

ASJC Scopus subject areas

General Medicine

Access to Document

10.1007/978-3-031-83533-9_52

Cite this

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abstract = "This is a case of a patients with T4N0 sinonasal malignant melanoma who had received two cycles of ipilimumab and nivolumab who subsequently developed inflammatory arthritis of bilateral knees related to ICI treatment. This patient received corticosteroids and sulfasalazine with no response, but achieved complete remission on tocilizumab. This therapeutic effect sustained over 2 years despite patient resumed nivolumab monotherapy for cancer recurrence while receiving tocilizumab as concurrent treatment.",

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AB - This is a case of a patients with T4N0 sinonasal malignant melanoma who had received two cycles of ipilimumab and nivolumab who subsequently developed inflammatory arthritis of bilateral knees related to ICI treatment. This patient received corticosteroids and sulfasalazine with no response, but achieved complete remission on tocilizumab. This therapeutic effect sustained over 2 years despite patient resumed nivolumab monotherapy for cancer recurrence while receiving tocilizumab as concurrent treatment.

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KW - Immune checkpoint inhibitors

KW - Immune related adverse event

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Inflammatory Arthritis Post Immune Checkpoint Inhibitor Therapy

Abstract

Keywords

ASJC Scopus subject areas

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