TY - GEN
T1 - Intelligent clinical decision support systems for non-invasive bladder cancer diagnosis
AU - Floares, Alexandru G.
AU - Floares, Carmen
AU - Vermesan, Oana
AU - Popa, Tiberiu
AU - Williams, Michael
AU - Ajibode, Sulaimon
AU - Chang-Gong, Liu
AU - Lixia, Diao
AU - Jing, Wang
AU - Nicola, Traila
AU - Jackson, David
AU - Dinney, Colin
AU - Adam, Liana
PY - 2011
Y1 - 2011
N2 - The aim of this study was to find the set of biomarkers based on plasma microRNAs which can predict in a noninvasive way the diagnosis of bladder cancer. We presented here a methodology and the related concepts to develop intelligent molecular biomarkers using knowledge discovery in data and artificial intelligence methods. To the best of our knowledge, this is the first time when plasma miRNAs are combined using artificial intelligence and the prediction accuracy of the developed systems for medical decision support is the best published by now, some of them having even 100%.
AB - The aim of this study was to find the set of biomarkers based on plasma microRNAs which can predict in a noninvasive way the diagnosis of bladder cancer. We presented here a methodology and the related concepts to develop intelligent molecular biomarkers using knowledge discovery in data and artificial intelligence methods. To the best of our knowledge, this is the first time when plasma miRNAs are combined using artificial intelligence and the prediction accuracy of the developed systems for medical decision support is the best published by now, some of them having even 100%.
KW - artificial intelligence
KW - bladder cancer diagnosis
KW - microRNA
KW - noninvasive
UR - http://www.scopus.com/inward/record.url?scp=80051692683&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=80051692683&partnerID=8YFLogxK
U2 - 10.1007/978-3-642-21946-7_20
DO - 10.1007/978-3-642-21946-7_20
M3 - Conference contribution
AN - SCOPUS:80051692683
SN - 9783642219450
T3 - Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
SP - 253
EP - 262
BT - Computational Intelligence Methods for Bioinformatics and Biostatistics - 7th International Meeting, CIBB 2010, Revised Selected Papers
T2 - 7th International Meeting on Computational Intelligence Methods for Bioinformatics and Biostatistics, CIBB 2010
Y2 - 16 September 2010 through 18 September 2010
ER -