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Interaction of indoleamine-2,3-dioxyagnase and CD4+ CD25+ regulatory T cells in tumor immune escape

  • Hui Wang
  • , Ke Pan
  • , Jian Chuan Xia

    Research output: Contribution to journalReview articlepeer-review

    Abstract

    There are numerous factors involved in the tumor evasion from immune surveillance. Recently, considerable attention has been given to indoleamine 2,3-dioxygenase (IDO) and CD4+CD25+ regulatory T cells (Tregs). The interaction between the two may play a crucial role in tumor immune escape. This article reviews the correlation between IDO and Tregs in immune escape of tumors.

    Original languageEnglish (US)
    Pages (from-to)184-187
    Number of pages4
    JournalChinese Journal of Cancer
    Volume28
    Issue number2
    StatePublished - 2009

    Keywords

    • CD4+CD25+ regulatory T cells
    • Immune escape
    • Indoleamine-2,3-dioxygenase
    • Tumor

    ASJC Scopus subject areas

    • Oncology

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