Intraosseous hibernoma

Rajendra Kumar; Michael T. Deaver; Bogdan A. Czerniak; John E. Madewell

doi:10.1007/s00256-010-1079-x

Intraosseous hibernoma

Rajendra Kumar, Michael T. Deaver, Bogdan A. Czerniak, John E. Madewell

Pathology

Research output: Contribution to journal › Article › peer-review

30 Scopus citations

Abstract

We describe the imaging and pathological features of a rare case of sacral hibernoma that was discovered incidentally in a patient with low back pain. The benign-appearing, small intraosseous lesion in the sacrum was sclerotic on CT. MRI revealed that the lesion was heterogeneously hyperintense on T1W (lower in intensity than subcutaneous fat) and heterogeneously hypointense on fat-saturated T2W and STIR images. It showed mild heterogeneous enhancement on the post-contrast fat-saturated T1 MR images due to increased vascularity. A biopsy of the lesion was performed. The biopsy specimen demonstrated multivacuolated cells with immunohistochemical features of brown adipose tissue consistent with hibernoma.

Original language	English (US)
Pages (from-to)	641-645
Number of pages	5
Journal	Skeletal radiology
Volume	40
Issue number	5
DOIs	https://doi.org/10.1007/s00256-010-1079-x
State	Published - May 2011

Keywords

Benign bone tumor
Hibernoma
Intraosseous fatty tumor

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging

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10.1007/s00256-010-1079-x

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title = "Intraosseous hibernoma",

abstract = "We describe the imaging and pathological features of a rare case of sacral hibernoma that was discovered incidentally in a patient with low back pain. The benign-appearing, small intraosseous lesion in the sacrum was sclerotic on CT. MRI revealed that the lesion was heterogeneously hyperintense on T1W (lower in intensity than subcutaneous fat) and heterogeneously hypointense on fat-saturated T2W and STIR images. It showed mild heterogeneous enhancement on the post-contrast fat-saturated T1 MR images due to increased vascularity. A biopsy of the lesion was performed. The biopsy specimen demonstrated multivacuolated cells with immunohistochemical features of brown adipose tissue consistent with hibernoma.",

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AU - Kumar, Rajendra

AU - Deaver, Michael T.

AU - Czerniak, Bogdan A.

AU - Madewell, John E.

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N2 - We describe the imaging and pathological features of a rare case of sacral hibernoma that was discovered incidentally in a patient with low back pain. The benign-appearing, small intraosseous lesion in the sacrum was sclerotic on CT. MRI revealed that the lesion was heterogeneously hyperintense on T1W (lower in intensity than subcutaneous fat) and heterogeneously hypointense on fat-saturated T2W and STIR images. It showed mild heterogeneous enhancement on the post-contrast fat-saturated T1 MR images due to increased vascularity. A biopsy of the lesion was performed. The biopsy specimen demonstrated multivacuolated cells with immunohistochemical features of brown adipose tissue consistent with hibernoma.

AB - We describe the imaging and pathological features of a rare case of sacral hibernoma that was discovered incidentally in a patient with low back pain. The benign-appearing, small intraosseous lesion in the sacrum was sclerotic on CT. MRI revealed that the lesion was heterogeneously hyperintense on T1W (lower in intensity than subcutaneous fat) and heterogeneously hypointense on fat-saturated T2W and STIR images. It showed mild heterogeneous enhancement on the post-contrast fat-saturated T1 MR images due to increased vascularity. A biopsy of the lesion was performed. The biopsy specimen demonstrated multivacuolated cells with immunohistochemical features of brown adipose tissue consistent with hibernoma.

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KW - Intraosseous fatty tumor

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Intraosseous hibernoma

Abstract

Keywords

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