Is it time to routinely incorporate MRD into practice?

Research output: Contribution to journalReview article

1 Scopus citations

Abstract

Interest in detecting minimal/measurable residual disease (MRD) in acute myeloid leukemia (AML) has been increasing, but numerous issues need to be addressed if MRD assessment is to be routinely incorporated into practice. Assays, their reliability, standardization, and availability all must be considered, and a strategy developed to eradicate residual leukemia. This paper reviews some issues surrounding the routine incorporation of MRD assessment into practice.

Original languageEnglish (US)
Pages (from-to)396-400
Number of pages5
JournalBest Practice and Research: Clinical Haematology
Volume31
Issue number4
DOIs
StatePublished - Dec 2018

Keywords

  • AML
  • Acute myeloid leukemia
  • Assay
  • MFC
  • MRD
  • Minimal/measurable residual disease
  • Multi-parameter flow cytometry
  • NGS
  • Next-generation sequencing
  • RT-PCR
  • Reverse-transcriptase-polymerase-chain reaction

ASJC Scopus subject areas

  • Oncology
  • Clinical Biochemistry

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