Isolation of 6,7-demethylenedesoxypodophyllotoxin from Hernandia ovigera

C. Ito, T. Matsui, Tian-Shung Wu, H. Furukawa

    Research output: Contribution to journalArticle

    24 Scopus citations


    6,7-Demethylenedesoxypodophyllotoxin (1) was isolated from the seeds of Hernandia ovigera L. (Hernandiaceae) collected in Taiwan, together with several known lignans. This is the first example of the occurrence of 1 in a natural source. The assignments of the 13 C-nuclear magnetic resonance signals of several podophyllotoxin analogues isolated from this plant were also established by means of two-dimensional H-C correlation spectroscopy (COSY) and H-C long range COSY techniques.

    Original languageEnglish (US)
    Pages (from-to)1318-1321
    Number of pages4
    JournalChemical and Pharmaceutical Bulletin
    Issue number5
    StatePublished - Jan 1 1992

    ASJC Scopus subject areas

    • Chemistry(all)
    • Drug Discovery

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