TY - JOUR
T1 - Joint IARC/NCI International Cancer Seminar Series Report
T2 - Expert consensus on future directions for ovarian carcinoma research
AU - Virani, Shama
AU - Baiocchi, Glauco
AU - Bowtell, David
AU - Cabasag, Citadel J.
AU - Cho, Kathleen R.
AU - Fortner, Reneé T.
AU - Fujiwara, Keiichi
AU - Kim, Jae Weon
AU - Köbel, Martin
AU - Kurtz, Jean Emmanuel
AU - Levine, Douglas A.
AU - Menon, Usha
AU - Norquist, Barbara M.
AU - Pharoah, Paul D.P.
AU - Sood, Anil K.
AU - Tworoger, Shelley T.
AU - Wentzensen, Nicolas
AU - Chanock, Stephen J.
AU - Brennan, Paul
AU - Trabert, Britton
N1 - Publisher Copyright:
© 2021 Published by Oxford University Press.
PY - 2021/6/1
Y1 - 2021/6/1
N2 - Recently, ovarian cancer research has evolved considerably because of the emerging recognition that rather than a single disease, ovarian carcinomas comprise several different histotypes that vary by etiologic origin, risk factors, molecular profiles, therapeutic approaches and clinical outcome. Despite significant progress in our understanding of the etiologic heterogeneity of ovarian cancer, as well as important clinical advances, it remains the eighth most frequently diagnosed cancer in women worldwide and the most fatal gynecologic cancer. The International Agency for Research on Cancer and the United States National Cancer Institute jointly convened an expert panel on ovarian carcinoma to develop consensus research priorities based on evolving scientific discoveries. Expertise ranged from etiology, prevention, early detection, pathology, model systems, molecular characterization and treatment/clinical management. This report summarizes the current state of knowledge and highlights expert consensus on future directions to continue advancing etiologic, epidemiologic and prognostic research on ovarian carcinoma.
AB - Recently, ovarian cancer research has evolved considerably because of the emerging recognition that rather than a single disease, ovarian carcinomas comprise several different histotypes that vary by etiologic origin, risk factors, molecular profiles, therapeutic approaches and clinical outcome. Despite significant progress in our understanding of the etiologic heterogeneity of ovarian cancer, as well as important clinical advances, it remains the eighth most frequently diagnosed cancer in women worldwide and the most fatal gynecologic cancer. The International Agency for Research on Cancer and the United States National Cancer Institute jointly convened an expert panel on ovarian carcinoma to develop consensus research priorities based on evolving scientific discoveries. Expertise ranged from etiology, prevention, early detection, pathology, model systems, molecular characterization and treatment/clinical management. This report summarizes the current state of knowledge and highlights expert consensus on future directions to continue advancing etiologic, epidemiologic and prognostic research on ovarian carcinoma.
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U2 - 10.1093/carcin/bgab043
DO - 10.1093/carcin/bgab043
M3 - Review article
C2 - 34037709
AN - SCOPUS:85108742202
SN - 0143-3334
VL - 42
SP - 785
EP - 793
JO - Carcinogenesis
JF - Carcinogenesis
IS - 6
ER -