TY - JOUR
T1 - KDIGO Controversies Conference on onco-nephrology
T2 - understanding kidney impairment and solid-organ malignancies, and managing kidney cancer
AU - Porta, Camillo
AU - Bamias, Aristotelis
AU - Danesh, Farhad R.
AU - Dębska-Ślizień, Alicja
AU - Gallieni, Maurizio
AU - Gertz, Morie A.
AU - Kielstein, Jan T.
AU - Tesarova, Petra
AU - Wong, Germaine
AU - Cheung, Michael
AU - Wheeler, David C.
AU - Winkelmayer, Wolfgang C.
AU - Małyszko, Jolanta
AU - Abu-Alfa, Ali K.
AU - Amer, Hatem
AU - Beutel, Gernot
AU - Chapman, Jeremy
AU - Chen, Xiaohong
AU - Chudek, Jerzy
AU - Cosmai, Laura
AU - Danesi, Romano
AU - De Stefano, Filippo
AU - Iseki, Kunitoshi
AU - Jaimes, Edgar A.
AU - Jhaveri, Kenar D.
AU - Jurczyszyn, Artur
AU - Kazancioğlu, Rümeyza
AU - Kitchlu, Abhijat
AU - Kollmannsberger, Christian
AU - Lahoti, Amit
AU - Li, Yang
AU - Macía, Manuel
AU - Matsubara, Takeshi
AU - Mitropoulos, Dionysios
AU - Noiri, Eisei
AU - Perazella, Mark A.
AU - Ronco, Pierre
AU - Rosner, Mitchell H.
AU - Soler Romeo, Maria Jose
AU - Sprangers, Ben
AU - Stadler, Walter M.
AU - Stevens, Paul E.
AU - ladimír Tesař, Tesař
AU - Torres da Costa e Silva, Verônica
AU - Vesole, David H.
AU - Vijayan, Anitha
AU - Viklický, Ondřej
AU - Workeneh, Biruh T.
AU - Yanagita, Motoko
AU - Zakharova, Elena
N1 - Publisher Copyright:
© 2020 Kidney Disease:Improving Global Outcomes (KDIGO)
PY - 2020/11
Y1 - 2020/11
N2 - The association between kidney disease and cancer is multifaceted and complex. Persons with chronic kidney disease (CKD) have an increased incidence of cancer, and both cancer and cancer treatments can cause impaired kidney function. Renal issues in the setting of malignancy can worsen patient outcomes and diminish the adequacy of anticancer treatments. In addition, the oncology treatment landscape is changing rapidly, and data on tolerability of novel therapies in patients with CKD are often lacking. Caring for oncology patients has become more specialized and interdisciplinary, currently requiring collaboration among specialists in nephrology, medical oncology, critical care, clinical pharmacology/pharmacy, and palliative care, in addition to surgeons and urologists. To identify key management issues in nephrology relevant to patients with malignancy, KDIGO (Kidney Disease: Improving Global Outcomes) assembled a global panel of multidisciplinary clinical and scientific expertise for a controversies conference on onco-nephrology in December 2018. This report covers issues related to kidney impairment and solid organ malignancies as well as management and treatment of kidney cancer. Knowledge gaps, areas of controversy, and research priorities are described.
AB - The association between kidney disease and cancer is multifaceted and complex. Persons with chronic kidney disease (CKD) have an increased incidence of cancer, and both cancer and cancer treatments can cause impaired kidney function. Renal issues in the setting of malignancy can worsen patient outcomes and diminish the adequacy of anticancer treatments. In addition, the oncology treatment landscape is changing rapidly, and data on tolerability of novel therapies in patients with CKD are often lacking. Caring for oncology patients has become more specialized and interdisciplinary, currently requiring collaboration among specialists in nephrology, medical oncology, critical care, clinical pharmacology/pharmacy, and palliative care, in addition to surgeons and urologists. To identify key management issues in nephrology relevant to patients with malignancy, KDIGO (Kidney Disease: Improving Global Outcomes) assembled a global panel of multidisciplinary clinical and scientific expertise for a controversies conference on onco-nephrology in December 2018. This report covers issues related to kidney impairment and solid organ malignancies as well as management and treatment of kidney cancer. Knowledge gaps, areas of controversy, and research priorities are described.
KW - glomerular filtration rate
KW - nephrotoxicity
KW - oncology
KW - renal cell carcinoma
UR - http://www.scopus.com/inward/record.url?scp=85093980957&partnerID=8YFLogxK
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U2 - 10.1016/j.kint.2020.06.046
DO - 10.1016/j.kint.2020.06.046
M3 - Article
C2 - 33126977
AN - SCOPUS:85093980957
SN - 0085-2538
VL - 98
SP - 1108
EP - 1119
JO - Kidney International
JF - Kidney International
IS - 5
ER -