LC-MS in drug bioanalysis

Q. Alan Xu; Timothy L. Madden

doi:10.1007/978-1-4614-3828-1

LC-MS in drug bioanalysis

Q. Alan Xu, Timothy L. Madden

Research output: Book/Report › Book

12 Scopus citations

Abstract

Clinical pharmacology plays an important role in today's medicine. Due to the high sensitivity, selectivity, and affordability of a mass spectrometer (MS), the high performance liquid chromatography - mass spectrometry (LC-MS) analytical technique is widely used in the determination of drugs in human biological matrixes for clinical pharmacology. Specifically, LC-MS is used to analyze: anticancer drugs antidementia drugs antidepressant drugs antiepileptic drugs antifundal drug antimicrobial drugs antipsychotic drugs antiretroviral drugs anxiolytic/hypnotic drugs cardiac drugs drugs for addiction immunosuppressant drugs mood stabilizer drugs This book will primarily cover the various methods of validation for LC-MS techniques and applications used in modern clinical pharmacology.

Original language	English (US)
Publisher	Springer US
Number of pages	469
ISBN (Electronic)	9781461438281
ISBN (Print)	1461438276, 9781461438274
DOIs	https://doi.org/10.1007/978-1-4614-3828-1
State	Published - Nov 1 2012
Externally published	Yes

ASJC Scopus subject areas

General Chemistry

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10.1007/978-1-4614-3828-1

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AB - Clinical pharmacology plays an important role in today's medicine. Due to the high sensitivity, selectivity, and affordability of a mass spectrometer (MS), the high performance liquid chromatography - mass spectrometry (LC-MS) analytical technique is widely used in the determination of drugs in human biological matrixes for clinical pharmacology. Specifically, LC-MS is used to analyze: anticancer drugs antidementia drugs antidepressant drugs antiepileptic drugs antifundal drug antimicrobial drugs antipsychotic drugs antiretroviral drugs anxiolytic/hypnotic drugs cardiac drugs drugs for addiction immunosuppressant drugs mood stabilizer drugs This book will primarily cover the various methods of validation for LC-MS techniques and applications used in modern clinical pharmacology.

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LC-MS in drug bioanalysis

Abstract

ASJC Scopus subject areas

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