TY - GEN
T1 - Leision quantification in dual-modality mammography using expectation maximization with attenuation correction
AU - Li, Heng
AU - Zheng, Yibin
AU - More, Mitali J.
AU - Goodale, Patricia J.
AU - Williams, Mark B.
N1 - Copyright:
Copyright 2011 Elsevier B.V., All rights reserved.
PY - 2004
Y1 - 2004
N2 - Conventional x-ray/scintillation mammography does not provide the depth information necessary to quantify the location and concentration of lesion activities in breast tissue. Our group is developing a novel tomographic dual modality system that will provide 3D structural and functional information of the breast. Because of constraints on the gantry geometry and acquisition time, only a limited number of views on one side of the breast can be acquired. In addition, the scatter and attenuation of gamma rays by breast tissue is a major problem for the reconstruction. We present an expectation-maximization (EM) method which naturally takes into account all the factors of noise, limited views, scatter, and attenuation. In a preliminary phantom study our quantification technique obtained results agreeing well with the ground truth.
AB - Conventional x-ray/scintillation mammography does not provide the depth information necessary to quantify the location and concentration of lesion activities in breast tissue. Our group is developing a novel tomographic dual modality system that will provide 3D structural and functional information of the breast. Because of constraints on the gantry geometry and acquisition time, only a limited number of views on one side of the breast can be acquired. In addition, the scatter and attenuation of gamma rays by breast tissue is a major problem for the reconstruction. We present an expectation-maximization (EM) method which naturally takes into account all the factors of noise, limited views, scatter, and attenuation. In a preliminary phantom study our quantification technique obtained results agreeing well with the ground truth.
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M3 - Conference contribution
AN - SCOPUS:17144427005
SN - 0780383885
SN - 9780780383883
T3 - 2004 2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano
SP - 1392
EP - 1395
BT - 2004 2nd IEEE International Symposium on Biomedical Imaging
T2 - 2004 2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano
Y2 - 15 April 2004 through 18 April 2004
ER -