@inbook{3ea9afb778774d53a52a80c0010b3dd1,
title = "Limiting Dilution Tumor Initiation Assay: An In Vivo Approach for the Study of Cancer Stem Cells",
abstract = "Cancer stem cells (CSCs) are a small subpopulation of self-renewing cancer cells that are present within tumors. Calculating the frequency of tumor-initiating cells is important in the assessment of the number of CSCs present in a cell population. In this chapter, we present a protocol developed for quantification of CSCs from breast cancer tumors that can be adapted to CSCs from other types of tumors.",
keywords = "Cancer stem cells, In vivo, Limiting dilution tumor initiation, Tumor-initiating cell frequency",
author = "{den Hollander}, Petra and Robiya Joseph and Suhas Vasaikar and Kuburich, {Nick A.} and Deshmukh, {Abhijeet P.} and Mani, {Sendurai A.}",
note = "Publisher Copyright: {\textcopyright} 2022, Springer Science+Business Media, LLC, part of Springer Nature.",
year = "2022",
doi = "10.1007/978-1-0716-1979-7_38",
language = "English (US)",
series = "Methods in Molecular Biology",
publisher = "Humana Press Inc.",
pages = "547--554",
booktitle = "Methods in Molecular Biology",
}