Livistona extract inhibits angiogenesis and cancer growth

Maryam R. Sartippour, Canhui Liu, Zhi Ming Shao, Vay Liang Go, David Heber, Mai Nguyen

    Research output: Contribution to journalArticle

    17 Scopus citations

    Abstract

    In a screen for naturally occurring angiogenic inhibitors, we have identified an extract from the seed of the plant Livistona chinensis, which has potent anti-angiogenic and anti-tumor activity. The aqueous extract inhibits the in vitro proliferation of endothelial cells and multiple tumor cell lines including mouse fibrosarcoma and human breast and colon cancer. In mouse experiments, this extract suppresses the growth of the subcutaneous fibrosarcoma tumors. When the seed is separated into different components, the shell including the seed skin appears more potent than the inner kernel in tumor suppression. Our results suggest that the extract from the shell of Livistona chinensis may be a potential supplemental source for cancer treatment.

    Original languageEnglish (US)
    Pages (from-to)1355-1357
    Number of pages3
    JournalOncology reports
    Volume8
    Issue number6
    StatePublished - Dec 1 2001

    Keywords

    • Alternative medicine
    • Angiogenesis
    • Livistona

    ASJC Scopus subject areas

    • Oncology
    • Cancer Research

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  • Cite this

    Sartippour, M. R., Liu, C., Shao, Z. M., Go, V. L., Heber, D., & Nguyen, M. (2001). Livistona extract inhibits angiogenesis and cancer growth. Oncology reports, 8(6), 1355-1357.