Local-regional treatment of the patient with inflammatory breast cancer

Research output: Contribution to journalReview articlepeer-review

Abstract

Inflammatory breast cancer (IBC) is a diagnosis based on a constellation of clinical features including a rapid onset of breast erythema and edema (peau d’orange) of a third or more of the skin of the breast and with a palpable border to the edema. Incidence has increased although it makes up only 1–4 % of all breast cancer diagnoses. In spite of some encouraging recent clinical outcome data, published local-regional control rates are consistently lower than expected in non-IBC and are of particular concern in this disease that readily progresses locally to carcinoma en cuirasse. With a focus on radiotherapy, this review provides a critical evaluation of the recent literature evaluating local-regional treatment of IBC, highlights new findings in the local-regional management of IBC, and offers an introduction to future directions regarding the optimal treatment and management of IBC.

Original languageEnglish (US)
Pages (from-to)37-42
Number of pages6
JournalCurrent Breast Cancer Reports
Volume7
Issue number1
DOIs
StatePublished - Mar 28 2015

Keywords

  • Breast cancer
  • DNA repair
  • Immunotherapy
  • Inflammatory breast cancer
  • Metastatic disease
  • Mevalonic acid
  • Modified radical mastectomy
  • PARP inhibitor
  • Post-mastectomy
  • Radiation therapy
  • Radiosensitizer
  • Recurrence
  • Statin
  • Stem cells

ASJC Scopus subject areas

  • Oncology

Fingerprint

Dive into the research topics of 'Local-regional treatment of the patient with inflammatory breast cancer'. Together they form a unique fingerprint.

Cite this