Magnetic resonance imaging-guided biopsy in the musculoskeletal system using a cylindrical 1.5-T magnetic resonance imaging unit

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8 Scopus citations


OBJECTIVES: The objective of this study was to report a single-center experience with magnetic resonance imaging (MRI)-guided biopsy in the musculoskeletal system using a closed-bore, cylindrical, high-magnetic-field (1.5-T) MRI unit. METHODS: From May 2010 to July 2011, 100 consecutive MRI-guided biopsy sessions were undertaken for musculoskeletal lesions in 97 patients. Patient demographics, tumor characteristics, and biopsy techniques were recorded. Biopsy results, treatment outcomes, and follow-up imaging studies were reviewed. RESULTS: Biopsy procedures were technically successful in 99 cases (99%). Despite a mean body mass index of 30 kg/m2, all patients fit within the bore of the magnet. There were 69 soft-tissue and 31 bone tumors. Most patients had both tissue core (n = 93) and fine-needle aspiration (n = 84) biopsies. All lesions were adequately imaged, localized, and targeted using rapid balanced steady-state free precession imaging (89%), fast T1 (4%), or combination of the 2 techniques (7%). A prototype real-time imaging sequence was used in 29 cases (29%) to guide biopsy needle insertion. There were no major complications. Sensitivity, specificity, and overall accuracy were 97%, 100%, and 97.6%, respectively. CONCLUSIONS: Magnetic resonance imaging-guided biopsy in a closed-bore, high-field-strength magnet is a safe, easy, and effective technique for evaluation of musculoskeletal lesions. Ideally, the MRI suite should be equipped with an in-room radiofrequency-shielded monitor and a communication system. However, surface coils with adequate opening to grant access to the biopsy site, MRI-compatible needles, and MRI-compatible patient monitoring devices are absolutely necessary to perform MRI-guided biopsies.

Original languageEnglish (US)
Pages (from-to)189-196
Number of pages8
JournalTopics in Magnetic Resonance Imaging
Issue number4
StatePublished - Aug 1 2011


  • Biopsy
  • Bone
  • MRI-guided
  • Musculoskeletal
  • Soft tissue
  • Tumor

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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