TY - JOUR
T1 - Malignant ectomesenchymoma in the wrist of a child
T2 - Case report and review of the literature
AU - Oppenheimer, Orit
AU - Athanasian, Edward
AU - Meyers, Paul
AU - Antonescu, Cristina R.
AU - Gorlick, Richard
N1 - Copyright:
Copyright 2017 Elsevier B.V., All rights reserved.
PY - 2005/1
Y1 - 2005/1
N2 - Malignant ectomesenchymomas, rare and potentially aggressive tumors, occur in children and exhibit mesenchymal and neuroectodermal components. This report describes the first patient diagnosed with a malignant ectomesenchymoma of the hand. The patient was a 17-month-old male who developed a hypothenar mass on his left hand that was surgically excised. Microscopic evaluation revealed ganglioneuroblastic, rhabdomyosarcomatous, and chondrosarcomatous elements. Following excisional biopsy he was treated with cyclophosphamide, doxorubicin, vincristine, ifosfamide, and etoposide. After 3 courses of chemotherapy the patient had a wide reexcision with no residual tumor. The patient is 4 years from diagnosis, without evidence of disease.
AB - Malignant ectomesenchymomas, rare and potentially aggressive tumors, occur in children and exhibit mesenchymal and neuroectodermal components. This report describes the first patient diagnosed with a malignant ectomesenchymoma of the hand. The patient was a 17-month-old male who developed a hypothenar mass on his left hand that was surgically excised. Microscopic evaluation revealed ganglioneuroblastic, rhabdomyosarcomatous, and chondrosarcomatous elements. Following excisional biopsy he was treated with cyclophosphamide, doxorubicin, vincristine, ifosfamide, and etoposide. After 3 courses of chemotherapy the patient had a wide reexcision with no residual tumor. The patient is 4 years from diagnosis, without evidence of disease.
KW - Chemotherapy
KW - Malignant ectomesenchymoma
KW - Pediatric tumors
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U2 - 10.1177/106689690501300117
DO - 10.1177/106689690501300117
M3 - Review article
C2 - 15735865
AN - SCOPUS:13544268704
SN - 1066-8969
VL - 13
SP - 113
EP - 116
JO - International Journal of Surgical Pathology
JF - International Journal of Surgical Pathology
IS - 1
ER -