Malignant neoplasia of the sex skin in 2 chimpanzees (Pan troglodytes)

Amanda P. Beck; Elizabeth R. Magden; Stephanie J. Buchl; Wallace B. Baze

Malignant neoplasia of the sex skin in 2 chimpanzees (Pan troglodytes)

Amanda P. Beck, Elizabeth R. Magden, Stephanie J. Buchl, Wallace B. Baze

Research output: Contribution to journal › Article › peer-review

Abstract

This report describes 2 cases of spontaneous malignant neoplasia within the sex skin of aged female chimpanzees. In both cases, the initial presentation resembled nonhealing traumatic wounds to the sex skin, with different degrees of infection, ulceration, and tissue necrosis. Histopathology of the lesions confirmed the diagnosis of squamous cell carcinoma in one case and of adenocarcinoma with metastasis in the other. Advanced age and previous trauma likely contributed to the development of the neoplasias in both cases; long-term sun exposure may also have contributed to the development of the squamous cell carcinoma. To our knowledge, these 2 cases represent the first reports of sex skin neoplasia in chimpanzees.

Original language	English (US)
Pages (from-to)	154-161
Number of pages	8
Journal	Comparative medicine
Volume	66
Issue number	2
State	Published - Apr 2016

Keywords

SCC
Squamous cell carcinoma

ASJC Scopus subject areas

General Biochemistry, Genetics and Molecular Biology
General Veterinary

Cite this

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title = "Malignant neoplasia of the sex skin in 2 chimpanzees (Pan troglodytes)",

abstract = "This report describes 2 cases of spontaneous malignant neoplasia within the sex skin of aged female chimpanzees. In both cases, the initial presentation resembled nonhealing traumatic wounds to the sex skin, with different degrees of infection, ulceration, and tissue necrosis. Histopathology of the lesions confirmed the diagnosis of squamous cell carcinoma in one case and of adenocarcinoma with metastasis in the other. Advanced age and previous trauma likely contributed to the development of the neoplasias in both cases; long-term sun exposure may also have contributed to the development of the squamous cell carcinoma. To our knowledge, these 2 cases represent the first reports of sex skin neoplasia in chimpanzees.",

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N2 - This report describes 2 cases of spontaneous malignant neoplasia within the sex skin of aged female chimpanzees. In both cases, the initial presentation resembled nonhealing traumatic wounds to the sex skin, with different degrees of infection, ulceration, and tissue necrosis. Histopathology of the lesions confirmed the diagnosis of squamous cell carcinoma in one case and of adenocarcinoma with metastasis in the other. Advanced age and previous trauma likely contributed to the development of the neoplasias in both cases; long-term sun exposure may also have contributed to the development of the squamous cell carcinoma. To our knowledge, these 2 cases represent the first reports of sex skin neoplasia in chimpanzees.

AB - This report describes 2 cases of spontaneous malignant neoplasia within the sex skin of aged female chimpanzees. In both cases, the initial presentation resembled nonhealing traumatic wounds to the sex skin, with different degrees of infection, ulceration, and tissue necrosis. Histopathology of the lesions confirmed the diagnosis of squamous cell carcinoma in one case and of adenocarcinoma with metastasis in the other. Advanced age and previous trauma likely contributed to the development of the neoplasias in both cases; long-term sun exposure may also have contributed to the development of the squamous cell carcinoma. To our knowledge, these 2 cases represent the first reports of sex skin neoplasia in chimpanzees.

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KW - Squamous cell carcinoma

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Malignant neoplasia of the sex skin in 2 chimpanzees (Pan troglodytes)

Abstract

Keywords

ASJC Scopus subject areas

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