Abstract
Autopsy studies suggest that skull base metastases are likely underrecognized in patients with cancer. Patients frequently present with one or a combination of skull base clinical syndromes that manifest as pain or cranial neuropathy. Once a skull base metastasis is suspected, establishing a histologic diagnosis, dedicated imaging, and restaging (if appropriate) are the first steps in management. A multidisciplinary approach should then be used to identify the optimal histology-based treatment strategy, taking into account the burden of systemic disease. Finally, definitive treatment may include one or a combination of surgical management, radiation therapy, or chemotherapy.”
Original language | English (US) |
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Pages (from-to) | 659-666 |
Number of pages | 8 |
Journal | Neurosurgery clinics of North America |
Volume | 31 |
Issue number | 4 |
DOIs | |
State | Published - Oct 2020 |
Keywords
- Cancer
- Metastasis
- Skull-base
- Surgery
ASJC Scopus subject areas
- Surgery
- Clinical Neurology