Mapping of the genes encoding mouse prostaglandin D, E, and F and prostacyclin receptors

Tomo O. Ishikawa, Yoshitaka Tamai, Julie M. Rochelle, Masakazu Hirata, Tsunehisa Namba, Yukihiko Sugimoto, Atsushi Ichikawa, Shuh Narumiya, Makoto M. Taketo, Michael F. Seldin

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    Abstract

    Prostaglandins and prostacyclin are metabolites of arachidonic acid and exert a variety of actions to maintain local homeostasis in the body. Their actions are mediated by cell surface receptors specific to the respective ligands. Using a panel of interspecific backcross mice, we have mapped the prostaglandin D receptor gene (Ptgdr), prostaglandin E receptor subtype EP1 gene (Ptgerep1), prostaglandin F receptor gene (Ptgfr), and prostacyclin receptor gene (Ptgir). Ptgdr mapped to proximal Chr 14, Ptgfr mapped to distal Chr 3, Ptgerep1 mapped to middle Chr 8, and Ptgir mapped to proximal Chr 7.

    Original languageEnglish (US)
    Pages (from-to)285-288
    Number of pages4
    JournalGenomics
    Volume32
    Issue number2
    DOIs
    StatePublished - Mar 1 1996

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    ASJC Scopus subject areas

    • Genetics

    Cite this

    Ishikawa, T. O., Tamai, Y., Rochelle, J. M., Hirata, M., Namba, T., Sugimoto, Y., Ichikawa, A., Narumiya, S., Taketo, M. M., & Seldin, M. F. (1996). Mapping of the genes encoding mouse prostaglandin D, E, and F and prostacyclin receptors. Genomics, 32(2), 285-288. https://doi.org/10.1006/geno.1996.0118