Measuring prompt gamma ray emission during proton radiotherapy for assessment of treatment delivery and patient response

Jerimy C. Polf, Stephen Peterson, Daniel Robertson, Sam Beddar

Research output: Chapter in Book/Report/Conference proceedingConference contribution

6 Scopus citations

Abstract

In this paper, we present results from a study of characteristic prompt gamma rays produced in patients during proton beam radiotherapy. A Monte Carlo study was performed calculating both proton dose deposition and prompt gamma ray production within a patient during proton beam irradiation. Form these calculations, comparisons were made between dose deposition and prompt gamma ray production within the patient. Also, calculations were performed of the production of characteristic gamma rays emitted from excited oxygen nuclei as a function of oxygen concentration within irradiated tumor tissue. Results show that there is a strong correlation between dose deposition and prompt gamma ray production within the patient, and that the production of prompt characteristic oxygen gamma rays is directly proportional to the oxygen concentration within the irradiated tissue.

Original languageEnglish (US)
Title of host publicationApplication of Accelerators in Research and Industry - Twenty-First International Conference, CAARI 2010
Pages364-368
Number of pages5
DOIs
StatePublished - 2011
Event21st International Conference on Application of Accelerators in Research and Industry, CAARI 2010 - Fort Worth, TX, United States
Duration: Aug 8 2010Aug 13 2010

Publication series

NameAIP Conference Proceedings
Volume1336
ISSN (Print)0094-243X
ISSN (Electronic)1551-7616

Other

Other21st International Conference on Application of Accelerators in Research and Industry, CAARI 2010
Country/TerritoryUnited States
CityFort Worth, TX
Period8/8/108/13/10

Keywords

  • In-vivo dose verification
  • Prompt gamma ray emission
  • Proton radiotherapy

ASJC Scopus subject areas

  • General Physics and Astronomy

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