Membranous nephropathy in chronic lymphocytic leukemia responsive to ibrutinib: A case report

Anna Eve Turcotte, William F. Glass, Jamie S. Lin, Jan A. Burger

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

Membranous nephropathy (MN) is an uncommon renal presentation in patients with chronic lymphocytic leukemia (CLL), and as such, there is no standard therapy for these patients. A few cases of MN in CLL have been described with varying success in MN treatment involving alkylating agents and fludarabine. Here we report the first case of MN in a patient with CLL treated with ibrutinib with complete renal response. This presentation underlines the importance of recognizing rare glomerular diseases that may occur with CLL and offers a new therapeutic avenue to the treatment of CLL-associated MN.

Original languageEnglish (US)
Article number100377
JournalLeukemia Research Reports
Volume20
DOIs
StatePublished - Jan 2023

Keywords

  • Bruton tyrosine kinase
  • Case report
  • Chronic lymphocytic leukemia
  • Membranous nephropathy
  • Paraneoplastic

ASJC Scopus subject areas

  • Hematology
  • Oncology

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