Molecular imaging of carcinogenesis with immuno-targeted nanoparticles

K. Sokolov, J. Aaron, S. Kumar, V. Mack, T. Collier, L. Coghlan, A. Gillenwater, K. Adler Storthz, M. Follen, R. Richards Kortum

Research output: Contribution to journalConference articlepeer-review

5 Scopus citations

Abstract

Molecular characterization of cancer could have important clinical benefits such as earlier cancer detection based on molecular characterization, the ability to predict the risk of cancer progression, real time margin detection, the ability to rationally select molecular therapy and to monitor response to the therapy. We present a new class of molecular specific contrast agents for optical imaging of carcinogenesis in vivo - gold nanoparticles conjugated with monoclonal antibodies specific for cancer biomarkers.

Original languageEnglish (US)
Pages (from-to)5292-5295
Number of pages4
JournalAnnual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
Volume26 VII
StatePublished - 2004
EventConference Proceedings - 26th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2004 - San Francisco, CA, United States
Duration: Sep 1 2004Sep 5 2004

Keywords

  • Cancer imaging
  • Gold nanoparticles
  • Molecular imaging

ASJC Scopus subject areas

  • Signal Processing
  • Biomedical Engineering
  • Computer Vision and Pattern Recognition
  • Health Informatics

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