MRI controlled HIFU treatment of breast tissue

J. Spoo, I. Simiantonakis, J. Jenne, R. Rastert, C. Bohris, M. Hlavac, J. Debus, Peter Huber

Research output: Contribution to journalConference article

3 Citations (Scopus)

Abstract

A study was carried out to test the feasibility of Magnetic Resonance Imaging (MRI)-monitored focused ultrasound surgery (FUS or HIFU) for the treatment of breast grandular tissue in animals. Fifteen 'L'-shaped target volumes in the sheep breast were treated applying 30 to 128 ultrasound pulses at a frequency of 1.7 MHz and an electrical power of 25-75 W per pulse. Therapy was performed with a newly designed fully MRI compatible ultrasound therapy unit. Conventional T1w and T2w MR imaging was carried out for assessing therapy effects. After treatments, the animals were sacrificed and a histologic workout was made. Overall, the results indicate that the MR compatible FUS unit is feasible in breast tissue, therapeutic effects could be proved in both, radiologic imaging and histology.

Original languageEnglish (US)
Pages (from-to)1405-1408
Number of pages4
JournalProceedings of the IEEE Ultrasonics Symposium
Volume2
StatePublished - Dec 1 1999
Event1999 IEEE Ultrasonics Symposium - Caesars Tahoe, NV, USA
Duration: Oct 17 1999Oct 20 1999

Fingerprint

breast
magnetic resonance
therapy
Ultrasonics
Tissue
animals
Animals
sheep
Imaging techniques
Histology
histology
pulses
surgery
Surgery
Magnetic Resonance Imaging

ASJC Scopus subject areas

  • Acoustics and Ultrasonics

Cite this

Spoo, J., Simiantonakis, I., Jenne, J., Rastert, R., Bohris, C., Hlavac, M., ... Huber, P. (1999). MRI controlled HIFU treatment of breast tissue. Proceedings of the IEEE Ultrasonics Symposium, 2, 1405-1408.

MRI controlled HIFU treatment of breast tissue. / Spoo, J.; Simiantonakis, I.; Jenne, J.; Rastert, R.; Bohris, C.; Hlavac, M.; Debus, J.; Huber, Peter.

In: Proceedings of the IEEE Ultrasonics Symposium, Vol. 2, 01.12.1999, p. 1405-1408.

Research output: Contribution to journalConference article

Spoo, J, Simiantonakis, I, Jenne, J, Rastert, R, Bohris, C, Hlavac, M, Debus, J & Huber, P 1999, 'MRI controlled HIFU treatment of breast tissue', Proceedings of the IEEE Ultrasonics Symposium, vol. 2, pp. 1405-1408.
Spoo J, Simiantonakis I, Jenne J, Rastert R, Bohris C, Hlavac M et al. MRI controlled HIFU treatment of breast tissue. Proceedings of the IEEE Ultrasonics Symposium. 1999 Dec 1;2:1405-1408.
Spoo, J. ; Simiantonakis, I. ; Jenne, J. ; Rastert, R. ; Bohris, C. ; Hlavac, M. ; Debus, J. ; Huber, Peter. / MRI controlled HIFU treatment of breast tissue. In: Proceedings of the IEEE Ultrasonics Symposium. 1999 ; Vol. 2. pp. 1405-1408.
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