Mucoepidermoid carcinoma post−radioactive iodine treatment of papillary thyroid carcinoma: unique presentation and putative etiologic association

Karan Saluja; Randall T. Butler; Kristen B. Pytynia; Bihong Zhao; Ron J. Karni; Randal S. Weber; Adel K. El-Naggar

doi:10.1016/j.humpath.2017.04.019

Mucoepidermoid carcinoma post−radioactive iodine treatment of papillary thyroid carcinoma: unique presentation and putative etiologic association

Karan Saluja, Randall T. Butler, Kristen B. Pytynia, Bihong Zhao, Ron J. Karni, Randal S. Weber, Adel K. El-Naggar

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

We report the development of mucoepidermoid carcinomas of the parotid gland in 2 adult patients after a relatively short duration of radioactive iodine (RAI) treatment of papillary thyroid carcinoma. Both instances, together with those previously reported, underscore the selective nature of the mucoepidermoid carcinoma phenotype development in patients with papillary thyroid carcinoma as a consequence of RAI treatment. Efforts to alleviate salivary pathophysiologic damage by RAI in these patients are warranted.

Original language	English (US)
Pages (from-to)	189-192
Number of pages	4
Journal	Human Pathology
Volume	68
DOIs	https://doi.org/10.1016/j.humpath.2017.04.019
State	Published - Oct 2017

Keywords

Mucoepidermoid carcinoma
Papillary thyroid carcinoma
Radioactive iodine treatment
Salivary gland carcinoma
Secondary carcinoma

ASJC Scopus subject areas

Pathology and Forensic Medicine

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10.1016/j.humpath.2017.04.019

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title = "Mucoepidermoid carcinoma post−radioactive iodine treatment of papillary thyroid carcinoma: unique presentation and putative etiologic association",

abstract = "We report the development of mucoepidermoid carcinomas of the parotid gland in 2 adult patients after a relatively short duration of radioactive iodine (RAI) treatment of papillary thyroid carcinoma. Both instances, together with those previously reported, underscore the selective nature of the mucoepidermoid carcinoma phenotype development in patients with papillary thyroid carcinoma as a consequence of RAI treatment. Efforts to alleviate salivary pathophysiologic damage by RAI in these patients are warranted.",

keywords = "Mucoepidermoid carcinoma, Papillary thyroid carcinoma, Radioactive iodine treatment, Salivary gland carcinoma, Secondary carcinoma",

author = "Karan Saluja and Butler, {Randall T.} and Pytynia, {Kristen B.} and Bihong Zhao and Karni, {Ron J.} and Weber, {Randal S.} and El-Naggar, {Adel K.}",

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T1 - Mucoepidermoid carcinoma post−radioactive iodine treatment of papillary thyroid carcinoma

T2 - unique presentation and putative etiologic association

AU - Saluja, Karan

AU - Butler, Randall T.

AU - Pytynia, Kristen B.

AU - Zhao, Bihong

AU - Karni, Ron J.

AU - Weber, Randal S.

AU - El-Naggar, Adel K.

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N2 - We report the development of mucoepidermoid carcinomas of the parotid gland in 2 adult patients after a relatively short duration of radioactive iodine (RAI) treatment of papillary thyroid carcinoma. Both instances, together with those previously reported, underscore the selective nature of the mucoepidermoid carcinoma phenotype development in patients with papillary thyroid carcinoma as a consequence of RAI treatment. Efforts to alleviate salivary pathophysiologic damage by RAI in these patients are warranted.

AB - We report the development of mucoepidermoid carcinomas of the parotid gland in 2 adult patients after a relatively short duration of radioactive iodine (RAI) treatment of papillary thyroid carcinoma. Both instances, together with those previously reported, underscore the selective nature of the mucoepidermoid carcinoma phenotype development in patients with papillary thyroid carcinoma as a consequence of RAI treatment. Efforts to alleviate salivary pathophysiologic damage by RAI in these patients are warranted.

KW - Mucoepidermoid carcinoma

KW - Papillary thyroid carcinoma

KW - Radioactive iodine treatment

KW - Salivary gland carcinoma

KW - Secondary carcinoma

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JO - Human Pathology

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ER -

Mucoepidermoid carcinoma post−radioactive iodine treatment of papillary thyroid carcinoma: unique presentation and putative etiologic association

Abstract

Keywords

ASJC Scopus subject areas

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