Mucosal Ablation Techniques for Barrett's Esophagus and Early Esophageal Cancer

Research output: Contribution to journalReview articlepeer-review

6 Scopus citations

Abstract

Patients with esophageal intestinal metaplasia, or Barrett's esophagus, may undergo dysplastic changes that eventually lead to invasive adenocarcinoma. Endoscopic therapy in the form of radiofrequency ablation and cryoablation has been described as a minimally invasive intervention to halt this sequence of dysplasia to carcinoma. Studies demonstrate that the use of radiofrequency ablation and cryoablation is highly successful at eradicating intestinal metaplasia and dysplasia and reducing the risk of disease progression. Furthermore, these modalities also may be used in combination with endoscopic mucosal resection, or as stand-alone therapy, for the treatment of intramucosal carcinoma, potentially circumventing the need for surgery.

Original languageEnglish (US)
Pages (from-to)473-480
Number of pages8
JournalThoracic surgery clinics
Volume28
Issue number4
DOIs
StatePublished - Nov 1 2018

Keywords

  • Barrett's esophagus
  • Catheter ablation
  • Cryotherapy
  • Endoscopy
  • Esophageal neoplasm
  • Esophagoscopy
  • Metaplasia
  • Precancerous conditions

ASJC Scopus subject areas

  • Surgery
  • Pulmonary and Respiratory Medicine

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