TY - JOUR
T1 - Multimodality imaging for evaluating response to neoadjuvant chemotherapy in breast cancer
AU - Rauch, Gaiane M.
AU - Adrada, Beatriz Elena
AU - Kuerer, Henry Mark
AU - Van La Parra, Raquel F.D.
AU - Leung, Jessica W.T.
AU - Yang, Wei Tse
N1 - Publisher Copyright:
© American Roentgen Ray Society.
PY - 2017/2
Y1 - 2017/2
N2 - OBJECTIVE. Neoadjuvant chemotherapy is becoming the standard of care for patients with locally advanced breast cancer. Conventional imaging modalities used for the assessment of tumor response to neoadjuvant chemotherapy rely on changes in size or morphologic characteristics and, therefore, are inherently limited. CONCLUSION. Functional imaging technologies evaluate vascular, metabolic, biochemical, and molecular changes in cancer cells and have a unique ability to detect specific biologic tumor markers, assess therapeutic targets, predict early response to neoadjuvant chemotherapy, and guide individualized cancer therapy.
AB - OBJECTIVE. Neoadjuvant chemotherapy is becoming the standard of care for patients with locally advanced breast cancer. Conventional imaging modalities used for the assessment of tumor response to neoadjuvant chemotherapy rely on changes in size or morphologic characteristics and, therefore, are inherently limited. CONCLUSION. Functional imaging technologies evaluate vascular, metabolic, biochemical, and molecular changes in cancer cells and have a unique ability to detect specific biologic tumor markers, assess therapeutic targets, predict early response to neoadjuvant chemotherapy, and guide individualized cancer therapy.
KW - Breast MRI
KW - Breast PET
KW - Breast cancer
KW - Molecular breast imaging
KW - Neoadjuvant chemotherapy
UR - http://www.scopus.com/inward/record.url?scp=85010992330&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85010992330&partnerID=8YFLogxK
U2 - 10.2214/AJR.16.17223
DO - 10.2214/AJR.16.17223
M3 - Review article
C2 - 27809573
AN - SCOPUS:85010992330
SN - 0361-803X
VL - 208
SP - 290
EP - 299
JO - American Journal of Roentgenology
JF - American Journal of Roentgenology
IS - 2
ER -