TY - JOUR
T1 - Natural breast symmetry in preoperative breast cancer patients
AU - Cheong, Audrey L.
AU - Liu, Jun
AU - Reece, Gregory P.
AU - Nicklaus, Krista M.
AU - Catherine Bordes, Mary
AU - Hanson, Summer E.
AU - Markey, Mia K.
AU - Merchant, Fatima A.
N1 - Funding Information:
From the *Department of Electrical and Computer Engineering, University of Houston, Houston, Tex.; †Department of Plastic Surgery, The University of Texas MD Anderson Cancer Center, Houston, Tex.; ‡Department of Biomedical Engineering, The University of Texas at Austin, Austin, Tex.; §Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, Tex.; and ¶Department of Engineering Technology, University of Houston, Houston, Tex. Received for publication December 13, 2018; accepted April 17, 2019. Presented at the San Antonio Breast Cancer Symposium 2018, San Antonio, TX, December 3–8, 2018. This work was supported by grants from the US National Institutes of Health (R01CA143190 and R01CA203984). The data in this study come from a prospective Institutional Review Board–approved research project (Protocol Number 2010-0321) at The University of Texas MD Anderson Cancer Center, Houston, Texas. Copyright © 2019 The Authors. Published by Wolters Kluwer Health, Inc. on behalf of The American Society of Plastic Surgeons. This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.
PY - 2019/7/1
Y1 - 2019/7/1
N2 - Background: Plastic surgeons aim to achieve breast symmetry during cosmetic and reconstructive breast surgery. They rely on measures of breast size, position, and projection to determine and achieve breast symmetry, but normative data on symmetry in preoperative breast reconstruction patients are scarce. Methods: A statistical evaluation was performed to examine the relationship of breast symmetry to demographic and clinical factors such as age, body mass index (BMI), race, and cancer status in a sample population of 87 patients who were scheduled to undergo mastectomy and breast reconstruction. The sternal notch to nipple (SN-N) distance and breast volume were measured on three-dimensional images, and distance and volume ratios across the left and right breasts were compared to determine symmetry. Ptosis grades were recorded and grade agreement (match) across the left and right breasts was assessed to determine shape symmetry. Results: A substantial portion of women (41.4%) showed SN-N distance differences >5 mm and 50.6% exhibited a volume difference >50 mL between their right and left breasts. Multiple linear regression modeling did not show any association between age, BMI, and cancer status and the SN-N and volume ratios. Race showed an association with volume symmetry but not with SN-N symmetry. A higher BMI increased the likelihood of ptosis disagreement. Additionally, tumor size did not impact overall breast symmetry. Conclusion: This study provides normative data on the extent of breast asymmetry in preoperative patients that can guide physicians in setting realistic goals for reconstruction procedures and manage patients' expectations related to outcomes.
AB - Background: Plastic surgeons aim to achieve breast symmetry during cosmetic and reconstructive breast surgery. They rely on measures of breast size, position, and projection to determine and achieve breast symmetry, but normative data on symmetry in preoperative breast reconstruction patients are scarce. Methods: A statistical evaluation was performed to examine the relationship of breast symmetry to demographic and clinical factors such as age, body mass index (BMI), race, and cancer status in a sample population of 87 patients who were scheduled to undergo mastectomy and breast reconstruction. The sternal notch to nipple (SN-N) distance and breast volume were measured on three-dimensional images, and distance and volume ratios across the left and right breasts were compared to determine symmetry. Ptosis grades were recorded and grade agreement (match) across the left and right breasts was assessed to determine shape symmetry. Results: A substantial portion of women (41.4%) showed SN-N distance differences >5 mm and 50.6% exhibited a volume difference >50 mL between their right and left breasts. Multiple linear regression modeling did not show any association between age, BMI, and cancer status and the SN-N and volume ratios. Race showed an association with volume symmetry but not with SN-N symmetry. A higher BMI increased the likelihood of ptosis disagreement. Additionally, tumor size did not impact overall breast symmetry. Conclusion: This study provides normative data on the extent of breast asymmetry in preoperative patients that can guide physicians in setting realistic goals for reconstruction procedures and manage patients' expectations related to outcomes.
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U2 - 10.1097/GOX.0000000000002297
DO - 10.1097/GOX.0000000000002297
M3 - Article
C2 - 31942335
AN - SCOPUS:85075168052
SN - 2169-7574
VL - 7
JO - Plastic and Reconstructive Surgery - Global Open
JF - Plastic and Reconstructive Surgery - Global Open
IS - 7
M1 - e2297
ER -