TY - JOUR
T1 - Neuroendocrine influences on cancer progression
AU - Armaiz-Pena, Guillermo N.
AU - Cole, Steve W.
AU - Lutgendorf, Susan K.
AU - Sood, Anil K.
N1 - Funding Information:
Portions of the work presented in this article were supported by National Cancer Institute Grants ( CA110793 , CA109298 , CA140933 , CA104825 and U54CA151668 ), the Ovarian Cancer Research Fund Program Project Development Grant , The University of Texas MD Anderson Cancer Center Ovarian Cancer SPORE Grant ( P50CA083639 ), the Gynecologic Cancer Foundation, the Zarrow Foundation, the Marcus Foundation and the Betty Anne Asche Murray Distinguished Professorship.
PY - 2013/3/15
Y1 - 2013/3/15
N2 - During the past decade, new studies have continued to shed light on the role of neuroendocrine regulation of downstream physiological and biological pathways relevant to cancer growth and progression. More specifically, our knowledge of the effects of the sympathetic nervous system (SNS) on cancer biology has been greatly expanded by new data demonstrating how the cellular immune response, inflammatory processes, tumor-associated angiogenesis, and tumor cell invasion and survival converge to promote tumor growth. This review will summarize these studies, while synthesizing clinical, cellular and molecular research that has continued to unearth the biological events mediating the interplay between SNS-related processes and cancer progression.
AB - During the past decade, new studies have continued to shed light on the role of neuroendocrine regulation of downstream physiological and biological pathways relevant to cancer growth and progression. More specifically, our knowledge of the effects of the sympathetic nervous system (SNS) on cancer biology has been greatly expanded by new data demonstrating how the cellular immune response, inflammatory processes, tumor-associated angiogenesis, and tumor cell invasion and survival converge to promote tumor growth. This review will summarize these studies, while synthesizing clinical, cellular and molecular research that has continued to unearth the biological events mediating the interplay between SNS-related processes and cancer progression.
KW - Adrenergic receptors
KW - Behavioral stress
KW - Cancer
KW - Catecholamines
KW - Metastasis
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U2 - 10.1016/j.bbi.2012.06.005
DO - 10.1016/j.bbi.2012.06.005
M3 - Review article
C2 - 22728325
AN - SCOPUS:84875371181
SN - 0889-1591
VL - 30
SP - S19-S25
JO - Brain, behavior, and immunity
JF - Brain, behavior, and immunity
IS - SUPPL.
ER -