Abstract
Magnetic resonance guided focused ultrasound surgery (MRgFUS) has potential noninvasive effects on targeted tissue. MRgFUS integrates MRI and focused ultrasound surgery (FUS) into a single platform. MRI enables visualization of the target tissue and monitors ultrasound-induced effects in near real-time during FUS treatment. MRgFUS may serve as an adjunct or replace invasive surgery and radiotherapy for specific conditions. Its thermal effects ablate tumors in locations involved in movement disorders and essential tremors. Its nonthermal effects increase blood-brain barrier permeability to enhance delivery of therapeutics and other molecules.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 559-567 |
| Number of pages | 9 |
| Journal | Neurosurgery clinics of North America |
| Volume | 28 |
| Issue number | 4 |
| DOIs | |
| State | Published - Oct 2017 |
Keywords
- Brain
- Focused ultrasound
- Glioma
- MRgFUS
- Magnetic resonance–guided focused ultrasound surgery
ASJC Scopus subject areas
- Surgery
- Clinical Neurology
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