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New prodrugs of 9-(2-phosphonomethoxyethyl) adenine [pmea]: Synthesis and stability studies

  • S. Benzaria
  • , G. Gosselin
  • , H. Pelicano
  • , G. Maury
  • , J. L. Imbach

Research output: Contribution to journal › Article › peer-review

Abstract

The synthesis, and stability in different media of new PMEA prodrugs, with S-acyl-thioethyl (SATE) as enzyme-labile phosphonate protecting groups, are described in comparison with the already known Bis(POM)- and Bis(DTE)PMEA.

Original languageEnglish (US)
Pages (from-to)563-565
Number of pages3
JournalNucleosides and Nucleotides
Volume14
Issue number3-5
DOIs
StatePublished - May 1 1995
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry
  • Genetics

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