Nischarin regulates secretion of exosomes and cancer progression

Research output: Contribution to journalArticlepeer-review

5 Scopus citations

Abstract

The intercellular exchange of exosomesmayplay a regulatory function in tumor progression and metastasis. Maziveyi and colleagues demonstrated that Nischarin regulated the secretion of exosomes from breast cancer cells. Loss of Nischarin expression increased exosome production and promoted tumor cell growth and migration, supporting that Nischarin can influence the behavior of surrounding cancer cells. This study identified a novel function of the tumor suppressor Nischarin in exosome biology and cancer progression.

Original languageEnglish (US)
Pages (from-to)2099-2101
Number of pages3
JournalCancer Research
Volume79
Issue number9
DOIs
StatePublished - 2019

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

Fingerprint

Dive into the research topics of 'Nischarin regulates secretion of exosomes and cancer progression'. Together they form a unique fingerprint.

Cite this